Results 111 to 120 of about 6,339,291 (274)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

On the Presentation and Cayley Graph of the Bruck–Reilly Idealization Semigroup

open access: yesJournal of Mathematics
Transferring constructions between different algebraic structures often reveals deep connections and enables the application of techniques from one theory to another.
Suha Wazzan   +2 more
doaj   +1 more source

K-Theory of Endomorphism Rings and of Rings of Invariants

open access: yesJournal of Algebra, 1997
Let \(T\) be a ring, \(P\) a finitely generated \(T\)-module, and \(I\) the trace ideal of \(P\) in \(T\). The main general result of this interesting article asserts that \(K_0(\text{End }P_T)\) is isomorphic to a subgroup of \(K_0(T,I)\). This fact is then applied to the situation where a finite group \(G\) acts on a ring \(S\), with \(|G|^{-1}\in S\)
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

A note on analogue of Koethe conjecture in group theory

open access: yesМатематичні Студії
We give a negative answer to a question in group theory proposed by Vitalyi Sushchanskyy which is an analogue of Koethe conjecture in ring theory.
W. Holubowski
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Identifying Low-Frequency Tree-Ring Variation

open access: yes, 1991
I propose an approach to provide 95% confidence intervals for a chronology of low-frequency tree-ring variation so that a level of significance or importance for trends can be inferred.
Sheppard, Paul R.
core   +1 more source

Ring Theory

open access: yes, 2015
We offer lectures on ring algebra for elementary students prepared by Professor Dr.
openaire   +2 more sources

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