Results 91 to 100 of about 6,339,291 (274)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Approach To Analyse Of Reaction Forces In Ring–Traveller System

open access: yesAUTEX Research Journal, 2017
The paper presents the approach to analyse of reaction forces and contact pressure for ring-traveller system in twisting machine. The theory of the ballooning yarn has been adapted for the calculation of reactions, and the motion equation is developed ...
Beran Jaroslav, Konečna Miroslava
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Recent results in hyperring and hyperfield theory

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1988
This survey article presents some recent results in the theory of hyperfields and hyperrings, algebraic structures for which the “sum” of two elements is a subset of the structure.
Anastase Nakassis
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Multivalued Rings

open access: yesJournal of Mathematical Extension, 2015
V. M. Buchstaber, defined multivalued groups. We define multivalued ring and we show that some similar results in ring theory, hold for multivalued rings.
H. Behravesh
doaj  

The Nine Rings of the Galaxy LEDA 1313424

open access: yesThe Astrophysical Journal
The galaxy LEDA 1313424 has recently been discovered by I. Pasha et al. to have nine rings. The authors of the discovery paper interpret the rings to be the result of the passing of a smaller galaxy through the center of the LEDA galaxy 56 Myr ago.
Pierre Sikivie, Yuxin Zhao
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Linear Vibrations of Nanotube-Reinforced Composite Conical Shell with Ring Stiffener

open access: yesJournal of Mechanical Engineering
Linear vibrations of thin-walled structure, which consists of nanotube-reinforced conical shell and ring stiffeners, are analyzed. Ring is attached at the end of truncated conical shell. Such shell structure describes adapter of rocket.
Kostiantyn V. Avramov   +4 more
doaj   +1 more source

Stress-Dilatancy for Soils. Part IV: Experimental Validation for Simple Shear Conditions

open access: yesStudia Geotechnica et Mechanica, 2017
This paper validates the frictional state theory using published experimental data from simple, direct and ring shear tests. Simple shear is treated as a special case of plane strain conditions.
Szypcio Zenon
doaj   +1 more source

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