Results 81 to 90 of about 6,123,368 (267)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Selecting and Characterizing Tree-Ring Chronologies for Dendroclimatic Analysis
, 1975 A widely spaced grid of tree-ring chronologies most suitable for dendroclimatic analysis of western North America is selected objectively on the basis of 1) numbers in the sample, length in years, and site locations, 2) statistical characteristics of the
Fritts, Harold C., Shatz, David J.
core +3 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
An Updated List of Species Used in Tree-Ring Research
, 1993 During the past 100 years, researchers have investigated the potential of hundreds of tree and shrub species for use in applications of tree-ring research.
Grissino-Mayer, Henri D.
core +3 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
When is R[x] a principal ideal ring?
Revista Integración, 2018 Because of its interesting applications in coding theory, cryptography, and algebraic combinatoris, in recent decades a lot of attention has been paid to the algebraic structure of the ring of polynomials R[x], where R is a finite commutative ring with ...
Henry Chimal-Dzul, C. A. López-Andrade
doaj +1 more source
Nonstandard theory of Zariski rings [PDF]
Proceedings of the American Mathematical Society, 1971 Let *R be an enlargement (in the sense of A. Robinson) of a Zariski ring (R, A), let ,u be the monad of zero in *R when R is given the A-adic topology and set R, equal to the qtuotient ring *R/l. It is shown that (R, R,) is a flat couple, and R, is Noetherian if and only if it is semilocal. Furthermore, if R is semilocal and A is the (Jacobson) radical
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Approach To Analyse Of Reaction Forces In Ring–Traveller System
AUTEX Research Journal, 2017 The paper presents the approach to analyse of reaction forces and contact pressure for ring-traveller system in twisting machine. The theory of the ballooning yarn has been adapted for the calculation of reactions, and the motion equation is developed ...
Beran Jaroslav, Konečna Miroslava
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source