Results 41 to 50 of about 3,851 (271)

Splitting fields for torsion-free modules over discrete valuation rings, II

open access: yesJournal of Algebra, 1977
AbstractLet G be a finite rank torsion-free module over a discrete valuation ring V. A splitting field for G is a subfield K of the quotient field of the completion V∗ of V such that (V∗ ∩ K) ⊗ G is a completely decomposable (V∗ ∩ K)-module. Every such G has a splitting field which is a finitely generated extension of the quotient field Q of V. If K is
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Multiplication polynomials and relative Manin-Mumford [PDF]

open access: yes, 2015
After the introduction we prove in chapter 2 that the resultant of the standard multiplication polynomials $A_n,B_n$ of an elliptic curve in the form $y^2 = x^3+ax+b$ is
$(16\Delta)^{{n^2(n^2-1) \over 6}}$, where $\Delta=-(4a^3+27b^2)$ is the ...
Schmidt, Harry
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Primitive near-rings [PDF]

open access: yes, 1970
The theory of near-rings has arisen in a variety of ways. There is a natural desire to generalise the theory of rings and skew fields by relaxing some of their defining axioms.
Holcombe, William Michael Lloyd
core  

Symbolic Analysis for Boundary Problems: From Rewriting to Parametrized Groebner Bases [PDF]

open access: yes, 2010
We review our algebraic framework for linear boundary problems (concentrating on ordinary differential equations). Its starting point is an appropriate algebraization of the domain of functions, which we have named integro-differential algebras.
Regensburger, Georg   +4 more
core   +1 more source

Endomorphism rings and isogenies classes for Drinfeld A-modules of rank 2 over finite fields [PDF]

open access: yesComptes Rendus. Mathématique, 2006
For a Drinfeld module of rank 2, we discuss many analogy points with elliptic curves. More precisely, we study the characteristic polynomial of a Drinfeld module of rank 2 and use it to calculate the number of isogeny classes for such modules.
openaire   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Near-rings and near-ring modules [PDF]

open access: yes, 2017
Dickson [11], in 1905,first gave examples of finite nearfields, which, in 1907, were used by 0. Veblen and J.H. MaclaganWedderburn [26] to construct finite non-desarguesian and non-pascalian geometries.
Scott, Stuart Donald
core   +1 more source

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