Results 41 to 50 of about 323,118 (297)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Evolution of plant ribosome-inactivating proteins [PDF]
, 2010 This contribution presents an updated analysis of the evolution of ribosome-inactivating proteins (RIPs) in plants. All evidence suggests that an ancestor of modern seed plants developed the RIP domain at least 300 million years ago.
Peumans, Willy J, Van Damme, Els
core +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Flow-Based Rip Current Detection and Visualization
IEEE Access, 2022 Rip currents are like rivers of fast-moving water that can quickly carry the unwary out to sea. They are not easy to recognize, especially to the untrained observer.
Issei Mori +4 more
doaj +1 more source
Certifying the restricted isometry property is hard
, 2012 This paper is concerned with an important matrix condition in compressed sensing known as the restricted isometry property (RIP). We demonstrate that testing whether a matrix satisfies RIP is NP-hard.
Bandeira, Afonso S. +3 more
core +1 more source
Explicit constructions of RIP matrices and related problems [PDF]
, 2010 We give a new explicit construction of $n\times N$ matrices satisfying the Restricted Isometry Property (RIP). Namely, for some c>0, large N and any n satisfying N^{1-c} < n < N, we construct RIP matrices of order k^{1/2+c}.
Denka Kutzarova +10 more
core +6 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Rip current related drowning deaths and rescues in Australia 2004–2011 [PDF]
Natural Hazards and Earth System Sciences, 2013 Rip currents are a common hazard to beachgoers found on many beaches around the world, but it has proven difficult to accurately quantify the actual number of rip current related drowning deaths in many regions and countries.
B. Brighton +4 more
doaj +1 more source
Analyzing True Self-Reliance and Individualism [PDF]
, 2016 This essay analyzes the story of “Rip Van Winkle” by Washington Irving and criticizes Daniel Plung’s assessment of it in his article, “Rip Van Winkle’: Metempsychosis and the Quest for Self-Reliance.” In Plung’s article, he assesses that in the story of “
Greene, Stephanie
core +1 more source