Results 31 to 40 of about 694 (96)

Update on Diagnosis and Treatment of Gastrointestinal Stromal Tumors

Zhongliu Fangzhi Yanjiu, 2022
In recent years, with the emergence of new research evidence, the domestic and foreign guidelines in the field of gastrointestinal stromal tumors (GISTs) have been updated.
LIN Chen, ZHANG Zaizhong, WANG Lie
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Avances en tumores del estroma gastrointestinal: ¿hacia dónde vamos?

Cirugía y Cirujanos, 2022
Los tumores del estroma gastrointestinal (GIST) suponen el 1-2% de los tumores digestivos, siendo su localización más frecuente el estómago (55-60%) y el intestino delgado (30%).
Juan A. Fernández-Hernández, Sonia Cantín-Blázquez, Elena García-Somacarrera, Evaristo Varo-Pérez, José A. González-López, José M. Asencio-Pascual, Marta Mendiola, César Serrano, Eduardo García-Granero, Vicente Artigas-Raventós   +9 more
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Development and validation of an HPLC-FLD method for the determination of ripretinib in rat plasma and application to a pharmacokinetic study [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Ripretinib, an FDA-approved kinase inhibitor, has shown promise as a treatment for advanced gastrointestinal stromal tumors. Aims: To evaluate the pharmacokinetic profile of ripretinib, particularly in pre-clinical studies.
Ibrahim N. Tarawneh, Reham M. Abu Shmeis, Fadi M. Al-Foqha’a, Anas Alshishani, Jomana Al Hroot, Aref Zayed   +5 more
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Metastatic SDH-Deficient GIST Diagnosed during Pregnancy: Approach to a Complex Case

Current Oncology, 2022
Gastrointestinal stromal tumors (GISTs) account for 1% of GI neoplasms in adults, and epidemiological data suggest an even lower occurrence in pregnant women. The majority of GISTs are caused by KIT and PDGFRA mutations.
Anas Chennouf, Elie Zeidan, Martin Borduas, Maxime Noël-Lamy, John Kremastiotis, Annie Beaudoin   +5 more
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The management of metastatic GIST: current standard and investigational therapeutics

Journal of Hematology & Oncology, 2021
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. The majority of GISTs harbor gain of function mutations in either KIT or PDGFRα.
Ciara M. Kelly, Laura Gutierrez Sainz, Ping Chi   +2 more
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Advances in the management of gastrointestinal stromal tumors (GISTs)

Nowotwory, 2020
Gastrointestinal stromal tumors are rare neoplasms developing from cells of Cajal in the gastrointestinal tract. The mainstay of such tumors treatment is surgery, whenever possible. The therapeutic management of inoperable and metastatic disease is based
Monika Dudzisz-Śledź, Piotr Rutkowski
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2023 GEIS Guidelines for gastrointestinal stromal tumors

Therapeutic Advances in Medical Oncology, 2023
Gastrointestinal stromal tumor (GIST) is the most common malignant neoplasm of mesenchymal origin. GIST spans a wide clinical spectrum that ranges from tumors with essentially no metastatic potential to malignant and life-threatening spread diseases ...
César Serrano, Javier Martín-Broto, José Manuel Asencio-Pascual, José Antonio López-Guerrero, Jordi Rubió-Casadevall, Silvia Bagué, Xavier García-del-Muro, Juan Ángel Fernández-Hernández, Luís Herrero, Antonio López-Pousa, Andrés Poveda, Virginia Martínez-Marín   +11 more
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Renal adverse reactions of tyrosine kinase inhibitors in the treatment of tumours: A Bayesian network meta-analysis

Frontiers in Pharmacology, 2022
Objectives: Tumours remain a serious threat to human life. Following rapid progress in oncology research, tyrosine kinase inhibitors have been used to treat multiple tumour types. Given the great influence of kidneys on pharmacokinetics, renal toxicities
Ying Xiong, Ying Xiong, Qinxuan Wang, Yangyi Liu, Jingwen Wei, Xiaolei Chen   +5 more
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Ripretinib in Advanced Gastrointestinal Stromal Tumors: A Case Series and Literature Review from a Tertiary Cancer Center in India

Indian Journal of Medical and Paediatric Oncology
The therapeutic armamentarium for advanced gastrointestinal stromal tumors (GISTs) is rapidly evolving and demands personalized strategies due to its increasing complexity.
Ventrapragada Neelima, Shubham Sahni, Mangu Srinivas Bharadwaj, Shamim Ahmed Shamim, Sameer Rastogi   +4 more
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The Pharmacokinetic Effect of Itraconazole and Voriconazole on Ripretinib in Beagle Dogs by UPLC-MS/MS Technique [Corrigendum]

Drug Design, Development and Therapy, 2023
Wang H, Zhou C, Su Y, Gou K, Geng X, Qiu X. Drug Des Devel Ther. 2021;15:4865–4873. The authors have informed the journal that ripretinib was used in this study, not erdafitinib as indicated in parts of the paper.
Wang H, Zhou C, Su Y, Gou K, Geng X, Qiu X   +5 more
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