Results 121 to 130 of about 13,809 (235)
SCB has a robust RNAi response to injected dsRNA, but oral RNAi is less efficient. Nucleases do not appear to be responsible for the discrepancy, suggesting other factors are involved. Abstract BACKGROUND The striped cucumber beetle (SCB) is a serious pest of cucurbit crops, causing damage both by feeding on plants and by vectoring plant diseases ...
Emine Kaplanoglu +2 more
wiley +1 more source
Co-designing ab initio electronic structure methods on a RISC-V vector architecture. [PDF]
Grima Torres R +3 more
europepmc +1 more source
Integration of epigenetics into ecotoxicology: insights and fundamental research needs
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto +3 more
wiley +1 more source
In SH‐SY5Y cells, Methylglyoxal (MGO) reduces the intracellular dopamine content, up‐regulating the expression of proteins that modulate dopamine amount (MAO‐B, COMT, and α‐Syn). The MGO‐induced increase of COMT and α‐Syn expression is mediated by the reduction of miR‐214 and miR‐190a levels.
Alessandra Croce +9 more
wiley +1 more source
Guest‐Induced Activation of Multicolor Photoluminescence in Naphthalene Bisimide Liquid Crystals
Supramolecular host–guest design in naphthalene bisimide liquid crystals activates charge‐transfer emission and enables continuous tuning of color (511–685 nm) and lifetime, spanning prompt fluorescence, TADF, and RTP. Electron‐rich guests and Pt(II) complexes modulate emissive states, while co‐assembled NBI complexes create an energy‐transfer cascade ...
Johannes Nowarra +3 more
wiley +1 more source
Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley +1 more source
Do's and Don'ts When Visiting Circularly Polarized Luminescence
This perspective presents our insights into the principles, challenges, and opportunities of circularly polarized luminescence (CPL). Highlighting key concepts such as the dissymmetry factor (glum) and molecular design strategies, we discuss advances in CPL efficiency, emerging NIR emitters, solid‐state applications, and the growing role of theory and ...
Rafael G. Uceda +9 more
wiley +1 more source
New ACORAN and hipSYCL backends for RISC-V released and integrated in the EMDC v1.0 produced by WP3 (deliverable D3.1) and verified.
openaire +1 more source
Through simultaneous molecular and supramolecular engineering, an atomically precise nanocluster Cu16 with ambient ultrastability and ultrabright luminescence is constructed. Cu16 employs a dual structural/luminescent channel mechanism to achieve orthogonal responsiveness to five external stimuli, demonstrating multidimensional signalling capability ...
Leon Li‐Min Zhang +7 more
wiley +1 more source
SiCmiR Atlas: Single‐Cell miRNA Landscape Reveals Hub‐miRNA and Network Signatures in Human Cancers
SiCmiR predicts mature miRNA activity at single‐cell resolution using only 977 landmark genes, enabling scalable reconstruction of miRNA landscapes across diverse tissues and disease contexts. The SiCmiR Atlas integrates 9.36 million cells with analytical tools for hub‐miRNA discovery, biomarker prioritization, and regulatory network interrogation ...
Xiao‐Xuan Cai +12 more
wiley +1 more source

