Results 141 to 150 of about 13,809 (235)

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

Food Frontiers, Volume 7, Issue 2, March 2026.
This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu, Haoyu Li, Youyou Zheng, Xiaoqian Chen, Xuzhi Wan, Pan Zhuang, Wei Jia, Jianxin Yao, Haoyin Liu, Hongbo Shi, Xunan Lin, Yu Zhang, Jingjing Jiao   +12 more
wiley   +1 more source

Biochemical principles of miRNA targeting in flies. [PDF]

Nat Commun
Vega-Badillo J, Zamore PD, Jouravleva K.
europepmc   +1 more source

RNAi‐Based Pesticides: Genetic Innovations for Sustainable Crop Protection and One Health

Advanced Genetics, Volume 7, Issue 1, March 2026.
RNAi‐based pesticides offer precise, gene‐specific pest control using dsRNA to silence essential insect genes. Advanced delivery systems (nanoparticles, SIGS, HIGS) and multi‐omics‐driven target discovery enable effective, scalable, and environmentally safe crop protection, supporting biodiversity, human health, and One Health‐aligned sustainable ...
Jisheng Liu, Guy Smagghe
wiley   +1 more source

A TADF sensitizer moiety decorated MR emitter for enhancing spin-flip and anti-ACQ. [PDF]

Chem Sci
Wang X, Chen J, Ni S, Hu Y, Dai H, Xiao Z, Zhu W, Chou PT, Wu X.   +8 more
europepmc   +1 more source

RNA‐Based Therapies for Inherited Metabolic Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri, Sonam Gurung, Roopkatha Ghosh, Philippa B. Mills, Julien Baruteau, Haiyan Zhou   +5 more
wiley   +1 more source

A rigid donor unit strategy enables highly efficient narrowband blue multi-resonance thermally activated delayed fluorescence emitters. [PDF]

Chem Sci
Li D, Jiang S, Liu Q, Xu R, Yang GX, Li W, Su SJ, Jiang X.   +7 more
europepmc   +1 more source

RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets

MedComm, Volume 7, Issue 3, March 2026.
RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin, Zengkan Du, Shuya Jiang, Yan Liao, Changli Wang, Jiaqi Li, Haoling Zhang, Ting‐Ting Wei, Wangzheqi Zhang, Zui Zou   +9 more
wiley   +1 more source

Taming the Achilles' Heel: A Chemical and Structural Design to Address Off-Target Effects in siRNA Therapeutics. [PDF]

JACS Au
Parvathaneni RP, Krishnan N, Hempel N, Oommen OP, Varghese OP.   +4 more
europepmc   +1 more source

Impact of young carers' experiences on their mental health in emerging adulthood: Evaluation from a psychiatric perspective

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 1, March 2026.
Abstract Aim Previous research has primarily explored the negative impacts of caregiving on young carers (YCs)' mental health during childhood and adolescence, with limited focus on emerging adulthood. In particular, quantitative evidence on the development of depression in YCs in emerging adulthood is limited, especially regarding its persistence ...
Miki Ono, Yuuka Matsuzaki, Minori Sato, Jun Tsuchida, Akiyoshi Shimura, Yu Tamada, Chihiro Morishita, Jiro Masuya, Masayuki Kikkawa, Takeshi Inoue   +9 more
wiley   +1 more source

Domain-Specific Acceleration of Gravity Forward Modeling via Hardware-Software Co-Design. [PDF]

Micromachines (Basel)
Yang Y, Sun D, Ma Z, Gu W.
europepmc   +1 more source