Results 191 to 200 of about 10,270,316 (283)

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

open access: yesInternational Journal of Cancer, Volume 159, Issue 11, Page 2633-2652, 1 December 2026.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari   +10 more
wiley   +1 more source

Circular RNA circERBB2 Promotes Tumorigenesis via the miR‐1587/CBX2 Axis and Epigenetic Silencing of PTEN in Bladder Cancer Cells

open access: yesMedComm – Oncology, Volume 5, Issue 4, December 2026.
circERBB2, originating from backsplicing of ERBB2 pre‑mRNA, is robustly upregulated in bladder cancer (BLCA) and acts as a miR‑1587 sponge to derepress chromobox 2 (CBX2). CBX2 subsequently recruits EZH2 to catalyze H3K27me3 deposition at the PTEN promoter, epigenetically silencing this tumor suppressor and unleashing the PI3K/AKT/mTOR cascade to drive
Xiang Pan   +8 more
wiley   +1 more source

Investigating the Effect of Photovoice on the Resilience and Perceived Social Stigma of Patients With Type 1 Diabetes: A Study Protocol for a Randomized Controlled Trial

open access: yesHealth Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Patients with type 1 diabetes often experience high levels of perceived social stigma, which can severely impact their psychological resilience. Photovoice is an innovative visual participatory method, but its efficacy in this population remains unexplored.
Samaneh Taheri Tehrani   +2 more
wiley   +1 more source

Performance of five risk stratification tools for paediatric pneumonia against WHO scores using data from the PediCAP trial in sub-Saharan Africa [PDF]

open access: yesmedRxiv
Nalwanga D   +11 more
europepmc   +2 more sources

LINC01537 Regulates Malignant Phenotypes and Predicts Prognosis in Breast Cancer, and Its Bioinformatics Analysis

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
LINC01537 is upregulated in breast cancer, predicting poor prognosis; it acts as a ceRNA sponging miR‐138‐5p to upregulate EZH2, promoting breast cancer progression via this axis. ABSTRACT Breast cancer is a highly heterogeneous malignancy and constitutes one of the leading health threats to women globally.
Yuetong Guo, Libo Shi
wiley   +1 more source

Liquid Biopsy: Past, Present, and Future

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu   +8 more
wiley   +1 more source

Psychological Resilience and Quality of Life in Mycosis Fungoides Patients: A BIO-MUSE Study. [PDF]

open access: yesActa Derm Venereol
Johansson A   +5 more
europepmc   +1 more source

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