Taming the Achilles' Heel: A Chemical and Structural Design to Address Off-Target Effects in siRNA Therapeutics. [PDF]
Parvathaneni RP +4 more
europepmc +1 more source
Integrative Genomics Identifies Candidate Genes Underlying Trypanotolerance in Hybrid African Cattle
ABSTRACT Integrative genomics combines data from different omics sources to link genotypes and phenotypes with the aim of unravelling biological networks and pathways that undergird complex traits, particularly with respect to disease. In this respect, integrative genomics, leveraging population and functional genomic data, can be employed to ...
Gillian P. McHugo +10 more
wiley +1 more source
A screening tool to detect interstitial lung disease in systemic sclerosis: the ILD-RISC score. [PDF]
Bruni C +15 more
europepmc +1 more source
Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin +2 more
wiley +1 more source
Neuroendocrine tumours through an epigenetic lens: Emerging insights for diagnosis and treatment
Abstract Neuroendocrine tumours (NETs) are well‐differentiated epithelial neuroendocrine neoplasms that frequently develop in the small intestine, pancreas, and lungs. NETs originate from neuroendocrine cells specialized in hormone secretion implicated in a number of physiological processes.
Victoria Jacquot +4 more
wiley +1 more source
Germline fate determination by a single ARGONAUTE protein in <i>Ectocarpus</i>. [PDF]
Bukhanets V +9 more
europepmc +1 more source
Shaping future forests: how can ecophysiology support climate‐smart forest management?
Summary Climate change, particularly the associated increase in extreme events and disturbances, threatens the numerous environmental, social, and economic benefits that forests provide, both locally and globally. Heat and drought pose significant risks to forest ecosystems; the anticipated future climate is expected to exacerbate this trend ...
Arthur Gessler +18 more
wiley +1 more source
Heavy-atom functionalization promotes triplet-assisted charge-transfer exciton transport in organic cocrystals. [PDF]
Xiao Y +8 more
europepmc +1 more source
The inconsistent reporting and effect of resilience on outcomes following shoulder surgery. [PDF]
Pitts T, Aibinder WR.
europepmc +1 more source
Spin Coupling in Symmetric and Asymmetric Allyl and Phenalenyl Diradicals Bridged by an Inverted Singlet-Triplet System. [PDF]
Barreca MT, Di Maiolo F.
europepmc +1 more source

