Results 201 to 210 of about 10,270,316 (283)
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden +3 more
wiley +1 more source
Cell‐penetrating peptide‐peptide nucleic acid (CPP‐PNA) conjugates that target the oncogenic microRNA‐221‐5p were synthesised using Cu(I)‐catalysed azide‐alkyne cycloaddition (CuAAC) and disulfide‐mediated conjugation strategies. These constructs form highly stable, sequence‐selective PNA/RNA heteroduplexes and demonstrate preliminary antiproliferative
Martina Rotondo +3 more
wiley +1 more source
The Correlation of Psychological Symptoms, Quality of Life and Resilience in Patients with Recurrent Non-Melanoma Skin Cancer. [PDF]
Šimić G +5 more
europepmc +1 more source
Long non‐coding RNAs (lncRNAs) act as key regulators of economically important traits in livestock through diverse mechanisms including ceRNA networks, epigenetic regulation (X‐inactivation and imprinting) and liquid–liquid phase separation (LLPS).
Keyvan Khani +2 more
wiley +1 more source
σ‐Decoupled C9 fluorene‐framework topology control enables narrowband red MR emitters. SF‐BNO and PF‐BNO share the same BNO core, but differ in closed/open fluorene ring closure. SF‐BNO improves steric shielding and stability, while PF‐BNO enhances PLQY, orientation, and efficiency. Ex‐PSF and TE‐OLED architectures deliver ultra‐low efficiency roll‐off
Aradhya Rajput +7 more
wiley +2 more sources
Stress and Resilience Development in German Dental Students
ABSTRACT Introduction The study evaluated the effectiveness of a resilience training for dental students as a preventive measure for mental health and stress management, with consideration for its long‐term integration into dental education. Methods A 2‐day online resilience training was tailored to address specific stressors experienced by dental ...
Leonie X. Lin +3 more
wiley +1 more source
Tetraborylated Multiple Resonance Emitter Incorporating B─O Bond-Embedded π-Extension for Ultra-Narrowband and High-Efficiency Blue Devices. [PDF]
Zhao YC +5 more
europepmc +1 more source
Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress
ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee +5 more
wiley +1 more source
Alcohol-positive polytrauma patients: injury patterns, ICU resource use and mortality at a German Level I trauma center. [PDF]
Thiedemann C +7 more
europepmc +1 more source
4′‐ThioRNA was broadly tolerated across multiple positions in SARS‐CoV‐2‐targeting siRNAs, but full 4'‐thio modification of both strands caused a reduction in RNAi activity. Sense‐strand segmentation improved RNAi and antiviral activity, particularly when the nick was located at position 10 from the 5′‐end of the sense strand, thereby unlocking the ...
Yuhei Nogi +5 more
wiley +1 more source

