Results 201 to 210 of about 10,270,316 (283)

RNA degradomics and proteomics reveal the mechanism of dsProsβ1‐mediated proteasome targeting in Psylliodes chrysocephala

open access: yesPest Management Science, Volume 82, Issue 11, Page 10604-10614, November 2026.
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden   +3 more
wiley   +1 more source

Design, Synthesis and Biophysical Characterisation of CPP‐PNA Conjugates for Targeting Oncogenic microRNA‐221

open access: yesJournal of Peptide Science, Volume 32, Issue 11, November 2026.
Cell‐penetrating peptide‐peptide nucleic acid (CPP‐PNA) conjugates that target the oncogenic microRNA‐221‐5p were synthesised using Cu(I)‐catalysed azide‐alkyne cycloaddition (CuAAC) and disulfide‐mediated conjugation strategies. These constructs form highly stable, sequence‐selective PNA/RNA heteroduplexes and demonstrate preliminary antiproliferative
Martina Rotondo   +3 more
wiley   +1 more source

The Correlation of Psychological Symptoms, Quality of Life and Resilience in Patients with Recurrent Non-Melanoma Skin Cancer. [PDF]

open access: yesHealthcare (Basel)
Šimić G   +5 more
europepmc   +1 more source

Long Non‐Coding RNAs: Key Regulators of Economic Traits in Livestock From Mechanisms to Breeding Applications

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Long non‐coding RNAs (lncRNAs) act as key regulators of economically important traits in livestock through diverse mechanisms including ceRNA networks, epigenetic regulation (X‐inactivation and imprinting) and liquid–liquid phase separation (LLPS).
Keyvan Khani   +2 more
wiley   +1 more source

Fluorene‐Framework Engineering Enables Narrowband Red Multi‐Resonance Emitters for High‐Efficiency With Negligible Roll‐Off Toward BT.2020

open access: yesAngewandte Chemie, Volume 138, Issue 44, 26 October 2026.
σ‐Decoupled C9 fluorene‐framework topology control enables narrowband red MR emitters. SF‐BNO and PF‐BNO share the same BNO core, but differ in closed/open fluorene ring closure. SF‐BNO improves steric shielding and stability, while PF‐BNO enhances PLQY, orientation, and efficiency. Ex‐PSF and TE‐OLED architectures deliver ultra‐low efficiency roll‐off
Aradhya Rajput   +7 more
wiley   +2 more sources

Stress and Resilience Development in German Dental Students

open access: yesEuropean Journal of Dental Education, Volume 30, Issue 4, Page 1791-1798, November 2026.
ABSTRACT Introduction The study evaluated the effectiveness of a resilience training for dental students as a preventive measure for mental health and stress management, with consideration for its long‐term integration into dental education. Methods A 2‐day online resilience training was tailored to address specific stressors experienced by dental ...
Leonie X. Lin   +3 more
wiley   +1 more source

Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress

open access: yesPlant, Cell &Environment, Volume 49, Issue 11, Page 8437-8453, November 2026.
ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee   +5 more
wiley   +1 more source

Alcohol-positive polytrauma patients: injury patterns, ICU resource use and mortality at a German Level I trauma center. [PDF]

open access: yesInt J Emerg Med
Thiedemann C   +7 more
europepmc   +1 more source

4′‐ThioRNA Substitution and Sense‐Strand Segmentation for the Design of Functional Fully Modified siRNAs Targeting SARS‐CoV‐2

open access: yesChemistry – A European Journal, Volume 32, Issue 40, 27 October 2026.
4′‐ThioRNA was broadly tolerated across multiple positions in SARS‐CoV‐2‐targeting siRNAs, but full 4'‐thio modification of both strands caused a reduction in RNAi activity. Sense‐strand segmentation improved RNAi and antiviral activity, particularly when the nick was located at position 10 from the 5′‐end of the sense strand, thereby unlocking the ...
Yuhei Nogi   +5 more
wiley   +1 more source

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