Results 191 to 200 of about 31,060,844 (362)
Risk analysis for outpatient experimental infection as a pathway for affordable RSV vaccine development. [PDF]
NPJ VaccinesSiegal EZ, Schoevers JMH, Terstappen J, Delemarre EM, Johnston SL, van Beek LF, Bogaert D, Chiu C, Diavatopoulos DA, Ferreira DM, Gordon SB, Hayden FG, de Jonge MI, McCall MBB, McShane HI, Minassian AM, Openshaw PJM, Pollard AJ, Sattabongkot J, Read RC, Troelstra A, Viveen MC, Wilder-Smith A, van Wijk M, Bont LJ, Mazur NI. +25 moreeuropepmc +1 more sourceGenetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Nature Genetics, 2019 B. Kunkle, B. Grenier‐Boley, R. Sims, J. Bis, V. Damotte, A. Naj, A. Boland, M. Vronskaya, S. J. van der Lee, A. Amlie-Wolf, C. Bellenguez, A. Frizatti, V. Chouraki, E. Martin, K. Sleegers, N. Badarinarayan, J. Jakobsdóttir, K. Hamilton-Nelson, S. Moreno-Grau, R. Olaso, R. Raybould, Yuning Chen, A. Kuzma, M. Hiltunen, T. Morgan, S. Ahmad, B. Vardarajan, J. Epelbaum, P. Hoffmann, M. Boada, G. Beecham, Jean-Guillaume Garnier, D. Harold, A. Fitzpatrick, O. Valladares, Marie-Laure Moutet, A. Gerrish, A. Smith, L. Qu, D. Bacq, N. Denning, X. Jian, Yi Zhao, M. Del Zompo, Nick C Fox, S. Choi, I. Mateo, J. T. Hughes, H. Adams, J. Malamon, F. Sánchez-García, Y. Patel, Jennifer A. Brody, B. Dombroski, M. Naranjo, M. Daniilidou, G. Eiriksdottir, Shubhabrata Mukherjee, D. Wallon, J. Uphill, T. Aspelund, L. Cantwell, F. Garzia, D. Galimberti, E. Hofer, Mariusz Butkiewicz, B. Fin, E. Scarpini, C. Sarnowski, W. Bush, S. Meslage, J. Kornhuber, Charles C. White, Yuenjoo Song, R. Barber, S. Engelborghs, S. Sordon, D. Voijnovic, P. Adams, R. Vandenberghe, M. Mayhaus, L. Cupples, M. Albert, P. D. de Deyn, W. Gu, J. Himali, D. Beekly, A. Squassina, A. Hartmann, A. Orellana, D. Blacker, E. Rodríguez-Rodríguez, S. Lovestone, M. Garcia, R. Doody, Carmen Munoz-Fernadez, R. Sussams, Honghuang Lin, T. Fairchild, Y. A. Benito, C. Holmes, Hata Karamujić‐Čomić, M. Frosch, H. Thonberg, W. Maier, G. Roschupkin, B. Ghetti, V. Giedraitis, A. Kawalia, Shuo Li, R. Huebinger, L. Kilander, S. Moebus, I. Hernández, M. Kamboh, R. Brundin, J. Turton, Qiong Yang, M. Katz, L. Concari, J. Lord, A. Beiser, C. Keene, S. Helisalmi, I. Kloszewska, W. Kukull, A. Koivisto, A. Lynch, L. Tárraga, E. Larson, A. Haapasalo, B. Lawlor, T. Mosley, R. Lipton, V. Solfrizzi, M. Gill, W. Longstreth, T. Montine, V. Frisardi, M. Diez-Fairen, F. Rivadeneira, R. Petersen, V. Deramecourt, I. Álvarez, Francesca Salani, A. Ciaramella, E. Boerwinkle, E. Reiman, N. Fievet, J. Rotter, J. Reisch, O. Hanon, C. Cupidi, A. G. Andre Uitterlinden, D. Royall, C. Dufouil, R. Maletta, I. de Rojas, M. Sano, A. Brice, R. Cecchetti, P. George-Hyslop, K. Ritchie, M. Tsolaki, D. Tsuang, B. Dubois, D. Craig, Chuang‐Kuo Wu, H. Soininen, D. Avramidou, R. Albin, L. Fratiglioni, A. Germanou, L. Apostolova, L. Keller, M. Koutroumani, S. Arnold, F. Panza, O. Gkatzima, S. Asthana, D. Hannequin, P. Whitehead, C. Atwood, P. Caffarra, H. Hampel, I. Quintela, Á. Carracedo, L. Lannfelt, D. Rubinsztein, L. Barnes, F. Pasquier, L. Frölich, S. Barral, B. McGuinness, T. Beach, J. Johnston, J. Becker, P. Passmore, E. Bigio, J. Schott, T. Bird, J. Warren, B. Boeve, Michelle K. Lupton, J. Bowen, P. Proitsi, A. Boxer, J. Powell, J. Burke, J. Kauwe, J. Burns, M. Mancuso, J. Buxbaum, U. Bonuccelli, N. Cairns, A. McQuillin, C. Cao, G. Livingston, C. Carlson, N. Bass, C. Carlsson, J. Hardy, R. Carney, J. Bras, M. Carrasquillo, R. Guerreiro, M. Allen, H. Chui, E. Fisher, C. Masullo, E. Crocco, C. DeCarli, G. Bisceglio, M. Dick, Li Ma, R. Duara, N. Graff-Radford, Denis A. Evans, A. Hodges, K. Faber, M. Scherer, K. Fallon, M. Riemenschneider, D. Fardo, R. Heun, M. Farlow, H. Kölsch, S. Ferris, M. Leber, T. Foroud, I. Heuser, D. Galasko, I. Giegling, M. Gearing, M. Hüll, D. Geschwind, J. Gilbert, J. Morris, R. Green, K. Mayo, J. Growdon, T. Feulner, R. Hamilton, L. Harrell, D. Drichel, L. Honig, T. Cushion, M. Huentelman, P. Hollingworth, C. Hulette, B. Hyman, R. Marshall, G. Jarvik, A. Meggy, E. Abner, G. Menzies, Lee‐way Jin, G. Leonenko, L. Real, G. Jun, C. Baldwin, D. Grozeva, A. Karydas, G. Russo, J. Kaye, R. Kim, F. Jessen, N. Kowall, B. Vellas, J. Kramer, E. Vardy, F. LaFerla, K. Jöckel, J. Lah, M. Dichgans, J. Leverenz, D. Mann, A. Levey, S. Pickering-Brown, A. Lieberman, N. Klopp, K. Lunetta, H. Wichmann, C. Lyketsos, K. Morgan, D. Marson, K. Brown, F. Martiniuk, C. Medway, D. Mash, M. Nöthen, E. Masliah, N. Hooper, W. McCormick, A. Daniele, S. McCurry, A. Bayer, A. McDavid, J. Gallacher, A. Mckee, H. van den Bussche, M. Mesulam, C. Brayne, B. Miller, S. Riedel-Heller, C. Miller, Joshua W. Miller, A. Al-Chalabi, J. Morris, C. Shaw, A. Myers, J. Wiltfang, S. O'Bryant, J. Olichney, V. Álvarez, J. Parisi, A. Singleton, H. Paulson, J. Collinge, W. Perry, S. Mead, E. Peskind, D. Cribbs, M. Rossor, A. Pierce, N. Ryan, W. Poon, B. Nacmias, H. Potter, S. Sorbi, J. Quinn, E. Sacchinelli, A. Raj, G. Spalletta, M. Raskind, C. Caltagirone, P. Bossù, M. D. Orfei, B. Reisberg, R. Clarke, C. Reitz, A. Smith, J. Ringman, D. Warden, E. Roberson, G. Wilcock, E. Rogaeva, A. Bruni, H. Rosen, M. Gallo, R. Rosenberg, Y. Ben-Shlomo, M. Sager, P. Mecocci, A. Saykin, P. Pastor, M. Cuccaro, J. Vance, J. Schneider, L. S. Schneider, S. Slifer, W. Seeley, Amanda G. Smith, J. Sonnen, S. Spina, R. Stern, R. Swerdlow, Mitchell Tang, R. Tanzi, J. Trojanowski, J. Troncoso, V. V. Van Deerlin, L. V. Van Eldik, H. Vinters, J. Vonsattel, S. Weintraub, K. Welsh-Bohmer, K. Wilhelmsen, J. Williamson, T. Wingo, R. Woltjer, C. Wright, Chang-En Yu, Lei Yu, Y. Saba, A. Pilotto, M. Bullido, O. Peters, P. Crane, D. Bennett, P. Bosco, E. Coto, V. Boccardi, P. D. De Jager, A. Lleó, N. Warner, O. Lopez, M. Ingelsson, P. Deloukas, Carlos Cruchaga, C. Graff, R. Gwilliam, M. Fornage, A. Goate, P. Sánchez-Juan, P. Kehoe, N. Amin, N. Ertekin-Taner, C. Berr, S. Debette, S. Love, L. Launer, S. Younkin, J. Dartigues, C. Corcoran, M. Ikram, D. Dickson, G. Nicolas, D. Campion, J. Tschanz, H. Schmidt, H. Hakonarson, J. Clarimón, R. Munger, R. Schmidt, L. Farrer, C. van Broeckhoven, Michael C. O’Donovan, A. Destefano, L. Jones, J. Haines, J. Deleuze, M. Owen, V. Gudnason, R. Mayeux, V. Escott-Price, B. Psaty, A. Ramírez, Li-San Wang, A. Ruiz, C. V. van Duijn, P. Holmans, S. Seshadri, Julie Williams, P. Amouyel, G. Schellenberg, J. Lambert, M. Pericak-Vance +467 moresemanticscholar +1 more sourceCurrent trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor +6 morewiley +1 more sourceEarthing effects on mitochondrial function: ATP production and ROS generation
FEBS Open Bio, EarlyView.In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.Cecilia Giulivi, Richard Kotzwiley +1 more sourcePhenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines
FEBS Open Bio, EarlyView.Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis +6 morewiley +1 more sourceApplying disease risk analysis for conservation translocations in Argentina: A case study on marsh deer (Blastocerus dichotomus). [PDF]
PLoS OneWiemeyer GM, Uhart MM, Rodríguez Planes L, Rago V, Guillemi EC, Chang Reissig E, Raño M, Di Nucci D, Beldomenico PM, Peker S, Geffner L, Orozco MM. +11 moreeuropepmc +1 more source