Results 61 to 70 of about 36,912,388 (422)

How Do AI Timelines Affect Existential Risk? [PDF]

open access: yesarXiv, 2022
Superhuman artificial general intelligence could be created this century and would likely be a significant source of existential risk. Delaying the creation of superintelligent AI (ASI) could decrease total existential risk by increasing the amount of time humanity has to work on the AI alignment problem.
arxiv  

Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis

open access: yesAging, 2020
Currently, the number of patients with coronavirus disease 2019 (COVID-19) has increased rapidly, but relationship between comorbidity and patients with COVID-19 still not clear.
Bolin Wang   +3 more
semanticscholar   +1 more source

Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins [PDF]

open access: yes, 2020
IMPORTANCE There is an urgent need to improve lung cancer risk assessment because current screening criteria miss a large proportion of cases. OBJECTIVE To investigate whether a lung cancer risk prediction model based on a panel of selected circulating ...
Agudo, Antonio   +1 more
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Salmonella pathogenicity Island 1 undergoes decay in serovars adapted to swine and poultry

open access: yesMicrobiology Spectrum
Human salmonellosis is a high-priority foodborne disease worldwide. The main reservoir of Salmonella is livestock, mainly swine and poultry that are infected both by generalist serovars and serovars adapted to them.
Martina Tambassi   +8 more
doaj   +1 more source

Estimating probability of visual detection of exotic pests and diseases in the grains industry—An expert elicitation approach

open access: yesFrontiers in Ecology and Evolution, 2022
Participants in the grains industry undertake general surveillance monitoring of grain crops for early detection of pests and diseases. Evaluating the adequacy of monitoring to ensure successful early detection relies on understanding the probability of ...
Edith Arndt   +7 more
doaj   +1 more source

Complex Valued Risk Diversification [PDF]

open access: yes, 2018
Risk diversification is one of the dominant concerns for portfolio managers. Various portfolio constructions have been proposed to minimize the risk of the portfolio under some constrains including expected returns. We propose a portfolio construction method that incorporates the complex valued principal component analysis into the risk diversification
arxiv   +1 more source

Acceptable risks in Europe's proposed AI Act: Reasonableness and other principles for deciding how much risk management is enough [PDF]

open access: yesarXiv, 2023
This paper critically evaluates the European Commission's proposed AI Act's approach to risk management and risk acceptability for high-risk AI systems that pose risks to fundamental rights and safety. The Act aims to promote "trustworthy" AI with a proportionate regulatory burden.
arxiv  

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Probabilistic prediction of daily fire occurrence in the Mediterranean with readily available spatio-temporal data

open access: yesiForest - Biogeosciences and Forestry, 2017
The prediction of wildfire occurrence is an important component of fire management. We have developed probabilistic daily fire prediction models for a Mediterranean region of Europe (Cyprus) at the mesoscale, based on Poisson regression.
Papakosta P, Straub D
doaj   +1 more source

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