Results 91 to 100 of about 29,863,978 (304)

Artificial Intelligence in Data Science: Evaluating Forecasting Models for Solar Energy in the Amazon Basin

IEEE Access
Forecasting models employing machine learning (ML) and deep learning (DL) have become fundamental for assessing the technical feasibility of renewable energy systems.
Andre Luis Ferreira Marques, Ricardo Sbragio, Pedro Luiz Pizzigatti Correa, Marcelo Ramos Martins   +3 more
doaj   +1 more source

Risk Analysis in Civil Engineering [PDF]

, 2001
Until fairly recently there has been a tendency for structural engineering to be dominated by deterministic thinking, characterised in design calculations by the use of specified minimum material properties, specified load intensities and by prescribed procedures for computing stresses and deflections.
openaire  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Time-dependent toxicity and key toxic components of five neonicotinoid mixtures under environmental concentrations in the Yangtze River Basin

Environmental Chemistry and Ecotoxicology
Neonicotinoids (NEOs), as widely used insecticides, have raised increasing concerns regarding their ecological impacts. Current knowledge on the mixture toxicity of NEOs, particularly under environmental concentrations, remains insufficient.
Ting-Ting Ding, Xiao-Yu Wang, Shi-Lin Du, Hong-Yi Liang, Ya-Hui Zhang, Jin Zhang, Ming-Xiao Li, Shu-Shen Liu   +7 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Data mining-based screening of prevalent mixture systems in aquatic environments: A case study of antibiotics in the Yangtze River Basin

Ecotoxicology and Environmental Safety
Chemical pollution in real-world environment often involves exposure to combinations of thousands of chemicals. However, due to the vast number of possible combinations, it is nearly impossible to conduct comprehensive mixture toxicity tests and risk ...
Ting-Ting Ding, Shi-Lin Du, Hong-Yi Liang, Ya-Hui Zhang, Yong Tao, Ming-Xiao Li, Jin Zhang, Shu-Shen Liu   +7 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Classification And Analysis Of Risks In Software Engineering

, 2009
{"references": ["Rita C. Nienaber, Andries Barnard, \"A Generic AgentFramework to\nSupport the Various Software Project Management Processes\",\nInterdisciplinary Journal of Information, Knowledge, and Management, Vol. 2, 2007", "Ronald P. Higuera, Yacov Y.
Hoodat, Hooman, Rashidi, Hassan
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source