Results 81 to 90 of about 2,030,890 (306)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Optimizing Wireless Sensor Network Installations by Visibility Analysis on 3D Point Clouds

open access: yesISPRS International Journal of Geo-Information, 2019
In this paper, a MATLAB tool for the automatic detection of the best locations to install a wireless sensor network (WSN) is presented. The implemented code works directly on high-resolution 3D point clouds and aims to help in positioning sensors that ...
Teresa Gracchi   +5 more
doaj   +1 more source

Risk Analysis and Management in Software Engineering

open access: yesInternational Journal of Recent Technology and Engineering, 2019
Many programming building ventures have high dangers and disappointment rates amid their undertaking life. The undertakings primarily experience the ill effects of dangers created in programming advancement which are for the most part caused by operational dangers, innovative dangers, administration rehearses, hazards in accomplishing client ...
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Photocatalytic Degradation of Antibiotics Using Nanomaterials: Mechanisms, Applications, and Future Perspectives

open access: yesNanomaterials
Widespread antibiotic residues in aquatic environments pose escalating threats to ecological stability and human health, highlighting the urgent demand for effective remediation strategies.
Jianwei Liu   +8 more
doaj   +1 more source

Recent advances in Raman technology with applications in agriculture, food and biosystems: A review

open access: yesArtificial Intelligence in Agriculture, 2019
Raman technology, which covers Raman spectroscopy (RS) and its various derivative methods, has been widely applied in detection of various substances in agriculture, food and biosystems.
Shizhuang Weng   +7 more
doaj   +1 more source

Delta Hedging in Financial Engineering: Towards a Model-Free Approach [PDF]

open access: yes, 2010
Delta hedging, which plays a crucial r\^ole in modern financial engineering, is a tracking control design for a "risk-free" management. We utilize the existence of trends in financial time series (Fliess M., Join C.: A mathematical proof of the existence
Fliess, Michel, Join, Cédric
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Cross-Plant Transfer Assessment of Photovoltaic Performance Using Data-Driven Models and a Normalized Technical Factor

open access: yesIEEE Access
Assessing whether data-driven photovoltaic (PV) models can generalize beyond the plants used for training remains a critical challenge when operational data are available for only a limited number of installations.
Andre Luis Ferreira Marques   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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