Results 41 to 50 of about 2,014,035 (263)

Review article: Climate change impacts on dam safety [PDF]

open access: yesNatural Hazards and Earth System Sciences, 2018
Dams as well as protective dikes and levees are critical infrastructures whose associated risk must be properly managed in a continuous and updated process.
J. Fluixá-Sanmartín   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Phenomenological Nondimensional Parameter Decomposition to Enhance the Use of Simulation Modeling in Fire Probabilistic Risk Assessment of Nuclear Power Plants

open access: yesJournal of Nuclear Engineering
Simulation modeling is crucial in support of probabilistic risk assessment (PRA) for nuclear power plants (NPPs). There is a challenge, however, associated with simulation modeling that relates to the time and resources required for collecting data to ...
Sari Alkhatib   +7 more
doaj   +1 more source

Comprehensive Survey of Seismic Hazard at Geothermal Sites by a Meta-Analysis of the Underground Feedback Activation Parameter afb

open access: yesEnergies, 2021
Global efforts to tame CO2 emissions include the use of renewable energy sources, such as geo-energy harnessing. However, injecting pressurised fluids into the deep underground can induce earthquakes, hence converting CO2-related risk into seismic risk ...
Arnaud Mignan   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

EU-NICE, Eurasian University Network for International Cooperation in Earthquakes [PDF]

open access: yes, 2012
Despite the remarkable scientific advancements of earthquake engineering and seismology in many countries, seismic risk is still growing at a high rate in the world’s most vulnerable communities.
Braga, F.   +20 more
core   +1 more source

Mitigating Blast Hazards: Experimental Evaluation of Anti-Shatter Films and Catcher-Cable Systems on Conventional Windows

open access: yesBuildings
In light of terrorist attacks and accidents, the need for structural protection against explosive events has increased significantly in recent decades. Conventional unprotected windows pose a particularly high risk of injury to building occupants due to ...
Matthias Andrae   +4 more
doaj   +1 more source

Delta Hedging in Financial Engineering: Towards a Model-Free Approach [PDF]

open access: yes, 2010
Delta hedging, which plays a crucial r\^ole in modern financial engineering, is a tracking control design for a "risk-free" management. We utilize the existence of trends in financial time series (Fliess M., Join C.: A mathematical proof of the existence
Fliess, Michel, Join, Cédric
core   +3 more sources

"Last-Mile" preparation for a potential disaster [PDF]

open access: yes, 2009
Extreme natural events, like e.g. tsunamis or earthquakes, regularly lead to catastrophes with dramatic consequences. In recent years natural disasters caused hundreds of thousands of deaths, destruction of infrastructure, disruption of economic activity
Birkmann, J.   +16 more
core   +1 more source

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