Results 41 to 50 of about 1,977,008 (303)
Interactions between apparently ‘primary’ weather-driven hazards and their cost
Environmental Research Letters, 2015 A statistical analysis of the largest weather-driven hazards in the UK contradicts the typical view that each predominates in distinct events that do not interact with those of other hazard types (i.e., are ‘primary’); this potentially has implications ...
J K Hillier +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee +9 more
wiley +1 more source
Development of a digital twin operational platform using Python Flask
Data-Centric Engineering, 2022 The digital twin concept has developed as a method for extracting value from data, and is being developed as a new technique for the design and asset management of high-value engineering systems such as aircraft, energy generating plant, and wind ...
Matthew S. Bonney +6 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Strategies for robust renovation of residential buildings in Switzerland
Nature CommunicationsBuilding renovation is urgently required to reduce the environmental impact associated with the building stock. Typically, building renovation is performed by envelope insulation and/or changing the fossil-based heating system.
Alina Galimshina +5 more
doaj +1 more source
Editorial for the special issue: “Novel Solutions and Novel Approaches in Operational Research”
Business Systems Research, 2020 This special issue of Business Systems Research (SI of the BSR) is co-published by the Slovenian Society INFORMATIKA – Section for Operational Research (SSI-SOR) and highlights recent advances in Operations Research and Management Science (OR /MS), with ...
Drobne Samo +2 more
doaj +1 more source
Variability and uncertainty in empirical ground-motion prediction for probabilistic hazard and risk analyses [PDF]
, 2015 © The Author(s) 2015.The terms aleatory variability and epistemic uncertainty mean different things to people who routinely use them within the fields of seismic hazard and risk analysis.
A Kiureghian Der +7 more
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Linear response of the Greenland ice sheet's tidewater glacier terminus positions to climate
Journal of Glaciology, 2021 Gaining knowledge of tidewater glacier (TWG) margin evolution, solid ice flux and their responses to climate over large spatio-temporal scales provides valuable context for the projection of future Greenland ice sheet (GrIS) change.
Dominik Fahrner +4 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source