Results 51 to 60 of about 1,977,008 (303)

Geometry of martensite needles in shape memory alloys

open access: yesComptes Rendus. Mathématique, 2021
We study the geometry of needle-shaped domains in shape-memory alloys. Needle-shaped domains are ubiquitously found in martensites around macroscopic interfaces between regions which are laminated in different directions, or close to macroscopic ...
Conti, Sergio   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Rationality and dynamic consistency under risk and uncertainty [PDF]

open access: yes, 2013
For choice with deterministic consequences, the standard rationality hypothesis is ordinality - i.e., maximization of a weak preference ordering. For choice under risk (resp.
Hammond, Peter J., Zank, Horst
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Beliefs about EU 2030 climate commitments across public, expert, and policy audiences

open access: yesEnvironmental Research Letters
The European Union (EU) has adopted ambitious climate policies to reduce greenhouse gas emissions by 55% by 2030. While technical, economic, and political feasibility have been widely analyzed, far less is known about a critical enabling factor: whether ...
Loïc Berger   +8 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Tracking Economic Value of Products in Natural Settings: A Wireless EEG Study

open access: yesFrontiers in Neuroscience, 2018
Economic decision making refers to the process of individuals translating their preference into subjective value (SV). Little is known about the dynamics of the neural processes that underpin this form of value-based decision making and no studies have ...
Hannah Roberts   +10 more
doaj   +1 more source

Regulating nanotechnologies: risk, uncertainty and the global governance gap [PDF]

open access: yes, 2012
This article builds on research for a two-year project on nanotechnology regulation in the US and Europe (2008–09), which was funded by the European Commission.
Falkner, Robert, Jaspers, Nico
core   +1 more source

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