Results 81 to 90 of about 7,503,171 (257)
Comparative Study on Local Binary Patterns for Mammographic Density and Risk Scoring
Journal of Imaging, 2019 Breast density is considered to be one of the major risk factors in developing breast cancer. High breast density can also affect the accuracy of mammographic abnormality detection due to the breast tissue characteristics and patterns.
Minu George, Reyer Zwiggelaar
doaj +1 more source
sparr: Analyzing Spatial Relative Risk Using Fixed and Adaptive Kernel Density Estimation in R [PDF]
The estimation of kernel-smoothed relative risk functions is a useful approach to examining the spatial variation of disease risk. Though there exist several options for performing kernel density estimation in statistical software packages, there have ...
Tilman M. Davies +2 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Nonparametric Estimation of Risk-Neutral Densities [PDF]
This chapter deals with nonparametric estimation of the risk neutral density. We present three different approaches which do not require parametric functional assumptions on the underlying asset price dynamics nor on the distributional form of the risk ...
Wolfgang Karl Härdle +2 more
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Model Averaging Software for Dichotomous Dose Response Risk Estimation [PDF]
Model averaging has been shown to be a useful method for incorporating model uncertainty in quantitative risk estimation. In certain circumstances this technique is computationally complex, requiring sophisticated software to carry out the computation ...
A. John Bailer, Matthew W. Wheeler
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Estimation of Risk-Neutral Density Surfaces [PDF]
Option price data is often used to infer risk-neutral densities for future prices of an underlying asset. Given the prices of a set of options on the same underlying asset with different strikes and maturities, we propose a nonparametric approach for ...
L. N. Vicente +2 more
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
SensorsAs the number of European Union (EU) visitors grows, implementing novel border control solutions, such as mobile devices for passenger identification for land and sea border control, becomes paramount to ensure the convenience and safety of passengers ...
Maria Papaioannou +4 more
doaj +1 more source