Results 81 to 90 of about 9,072,523 (253)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis
Copyright 2024, © American Thyroid Association; Published by Mary Ann Liebert, Inc.Background: International guidelines recommend targeted screening to identify gestational thyroid dysfunction.
Oken E. +69 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
One risk factor predicts another risk factor
Li, Yiu-Tai, Chang, Wen-Hsun
openaire +3 more sources
Other title: Two Thousand Eight Behavioral Risk Factor Surveillance System
application/pdf; Report Preparation: Ghazala Perveen [and] Pratik Pandya.; "Funding for data collection of Anxiety and Depression module using the 2008 Behavioral Risk Factor Survey was provided by cooperative agreement # 1U58DP001968-01 from the Centers
Kansas. Bureau of Health Promotion.
core +1 more source
Other title: Two Thousand Eleven Behavioral Risk Factor Surveillance System
application/pdf; Report Preparation: Jeanie Santaularia. Report Supervision: Ghazala Perveen.; "Funding for data collection of Anxiety and Depression module using the 2011 Behavioral Risk Factor Survey was provided by cooperative agreement # 1U58S0000008-
Kansas. Bureau of Health Promotion.
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Cardiovascular Harm From Egg Yolk and Meat: More Than Just Cholesterol and Saturated Fat
J. David Spence +2 more
doaj +1 more source

