Results 91 to 100 of about 9,263,992 (362)

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Risk Factors of Pulmonary Tuberculosis Among Diabetes Mellitus Patients in Denpasar City [PDF]

, 2017
Background and Purpose: Tuberculosis (TB) is more common in developing countries, including Indonesia. Denpasar City contributes the most on the total number of TB patients in Bali Province. There is evidence on increased burden of diabetes mellitus (DM)
Duarsa, D. P. (Dyah), Putra, I. W. (I), Risna Dewi, D.P, Sagung Sawitri, A.A   +3 more
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Risk Factors for Recurrent Upper Gastrointestinal Tract Bleeding After Esophageal Varices Ligation on Patients with Liver Cirrhosis [PDF]

, 2004
Background: Upper gastrointestinal tract (GIT) bleeding on liver cirrhosis patients will increase morbidity and mortality. Recurrent bleeding\u27s risk rise after the first episode of variceal bleeding.
Akbar, N. (Nurul), Djojoningrat, D. (Dharmika), Hidayat, S. (Syarif), Prasetyo, S. (Sabarinah), Sukmana, N. (Nanang)   +4 more
core   +1 more source

GLOBAL RISK FACTORS

Journal of Business Economics and Management, 2006
The paper deals with a problem of solar and geomagnetic activity as global risk factors in financial risk management. The history of the idea of solar – earth relations is rather long (Hershel, 1804; Jevans, 1870 – Theory of Solar cycles, Chizhevsky, 1920 ‐ Theory of Heliotaraxy; Collins, 1965 etc.), but financial risk management does not use these ...
openaire   +4 more sources

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Assessment of intervention measures on trihalomethane in finished water by interrupted time series analysis

环境与职业医学
BackgroundThe Qingcaosha Reservoir is facing issues of algal blooms and eutrophication, and the resulting increase in the level of chlorination disinfection by-products in the water has been a major concern.
Yangyang REN, Hailei QIAN, Saifeng PEI, Xiaodong SUN, Zheng WU, Chen WU, Jingxian ZHOU, Aimin DU, Shaofeng SUI   +8 more
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Should socioeconomic factors be considered as traditional risk factors for cardiovascular disease, as confounders, or as risk modifiers? [PDF]

, 2008
A large number of studies show that cardiovascular disease and its traditional risk factors are associated with socioeconomic conditions. However, their etiological role in the development of cardiovascular outcomes is not always well understood ...
De Vogli, R., Marmot, M.
core  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source