Results 81 to 90 of about 9,263,992 (362)

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Risk factors for indigenous Campylobacter jejuni and Campylobacter coli infections in The Netherlands: a case-control study [PDF]

, 2010
A case-control study comprising 1315 Campylobacter jejuni cases, 121 Campylobacter coli cases and 3409 frequency-matched controls was conducted in The Netherlands in 2002-2003. Risk factors for both C. jejuni and C.
Brandhof, W.E., van den, Breukink, B.J., Doorduyn, Y., Duynhoven, Y.T.H.P., van, Pelt, W., van, Wagenaar, J.A.   +5 more
core   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Facile Fabrication of Flower-Like BiOI/BiOCOOH p–n Heterojunctions for Highly Efficient Visible-Light-Driven Photocatalytic Removal of Harmful Antibiotics

Nanomaterials, 2019
Novel heterojunction photocatalysts with remarkable photocatalytic capabilities and durability for degrading recalcitrant contaminants are extremely desired; however, their development still remains quite challenging.
Shijie Li, Bing Xue, Chunchun Wang, Wei Jiang, Shiwei Hu, Yanping Liu, Hengwei Wang, Jianshe Liu   +7 more
doaj   +1 more source

Occupational Risk Factors Associated with Perceived Central Nervous System Disorder among Printing Industry Workers In Medan [PDF]

, 2018
Background: Toluene is a colorless, water-insoluble liquid, aromatic hydro-carbon, with the smell associated with paint thinners. Toluene is used in the printing of colored illustrations in media such as catalogues and magazines.
Ashar, T. (Taufik ), Marganda, S. (Samuel ), Nurmaini, N. (Nurmaini)   +2 more
core  

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Effect of PHF-1 hyperphosphorylation on the seeding activity of C-terminal Tau fragments

Scientific Reports
Tau proteins as neurofibrillary tangles are one of the molecular hallmarks of Alzheimer’s disease (AD) and play a central role in tauopathies, a group of age-related neurodegenerative disorders.
Léa El Hajjar, Emmanuelle Boll, François-Xavier Cantrelle, Clarisse Bridot, Isabelle Landrieu, Caroline Smet-Nocca   +5 more
doaj   +1 more source

Total α and β radioactivity levels of source water in two areas of Shanghai from 2012 to 2022

Shanghai yufang yixue
ObjectiveThe purpose was to understand the background level of environmental radioactivity in the surrounding area of Qinshan Nuclear Power Plant and accumulate historical monitoring data of radioactivity in the environment， in order to detect and deal ...
HUANG Minpeng, QIAN Aijun, LUO Fajian, GAO Linfeng   +3 more
doaj   +1 more source

An Ecological Risk Model for Early Childhood Anxiety: The Importance of Early Child Symptoms and Temperament [PDF]

, 2010
Childhood anxiety is impairing and associated with later emotional disorders. Studying risk factors for child anxiety may allow earlier identification of at-risk children for prevention efforts.
Briggs-Gowan, Margaret J., Carter, Alice S., Mian, Nicholas D., Wainwright, Laurel   +3 more
core   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source