Results 101 to 110 of about 12,589,259 (348)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Downturn model risk: Another view of the global financial crisis
, 2010 Researchers and practitioners have spent ample resources modelling credit, explaining correlations between risk models as well as inputs and outputs.
Roesch, D, Scheule, H
core
Disaster Risk Reduction and Disaster Risk Management: State of Play in North Macedonia
This paper explores the state of disaster risk reduction (DRR) and disaster risk management (DRM) in North Macedonia, highlighting their theoretical, normative, and institutional aspects.
Ivanov, Aleksandar
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
A risk management framework for software engineering practice
, 2004 Formal risk analysis and management in software engineering is still an emerging part of project management. We provide a brief introduction to the concepts of risk management for software development projects, and then an overview of a new risk ...
Roy, G.G., G.G. Roy
core +1 more source
Postpartum psychosis: Risk factors identification
North American Journal of Medical Sciences, 2014 A better understanding of risk factors associated with postpartum psychosis may contribute to the better management.This study was to identify the risk factors contributing to postpartum psychosis.In this cross-sectional, case control study 100 patients of postpartum psychosis (PP) were compared with the healthy controls.
Upadhyaya, Suneet Kumar +2 more
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source