Results 111 to 120 of about 3,892,802 (298)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Estimating Risk Preferences in the Field [PDF]
, 2018 We survey the literature on estimating risk preferences using field data. We concentrate our attention on studies in which risk preferences are the focal object and estimating their structure is the core enterprise.
Barseghyan, Levon +3 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Utility company views of geothermal development [PDF]
The views of geothermal development from a utility company standpoint are presented. The impediments associated with such developments as required reliability and identification of risks are discussed.
Hinrichs, T. C.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Penerapan Hazard Identification Risk Assessment And Risk Control (Hirarc) sebagai Pengendalian Potensi Kecelakaan Kerja di Bagian Produksi Body Bus PT. X Magelang [PDF]
, 2016 Hazard Identification Risk Assessment and Risk Control (HIRARC) is a tool or a method to identify, assess or measure and control hazards based activities work in every workplace. PT.
Denny, H. M. (Hanifa) +2 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Горное оборудование и электромеханикаMining companies strive for maximum efficiency and safety. Quarry dump trucks (CS), being a key link, play a critical role in ensuring the smooth operation of the enterprise.
Chernyh V.G. +5 more
doaj +1 more source
Evaluation Report: Program to Reduce Depression Among High-Risk Patients [PDF]
, 2013 A program was funded in 2010 to improve the identification and treatment of patients at risk for depression at two community health centers. The project focused on patients with diabetes, chronic pain, mothers of newborns, and patients with a history of ...
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source