Results 121 to 130 of about 12,589,259 (348)

Child homicide: generating victim and suspect risk profiles [PDF]

open access: yes, 2015
Purpose– In England and Wales, on average one child every week is a victim of homicide. The purpose of this paper is to explore whether different victim-risk profiles and suspect variables can be differentiated for specific victim ages.Design/methodology/
Bryant, R.   +3 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

AIS-Based Multiple Vessel Collision and Grounding Risk Identification based on Adaptive Safety Domain

open access: yesJournal of Marine Science and Engineering, 2019
The continuous growth in maritime traffic and recent developments towards autonomous navigation have directed increasing attention to navigational safety in which new tools are required to identify real-time risk and complex navigation situations.
Azzeddine Bakdi   +3 more
semanticscholar   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Risk, Uncertainty and Monetary Policy [PDF]

open access: yes
The VIX, the stock market option-based implied volatility, strongly co-moves with measures of the monetary policy stance. When decomposing the VIX into two components, a proxy for risk aversion and expected stock market volatility (“uncertainty”), we ...
Marie Hoerova   +2 more
core  

Identification of "at-risk" students for prevention and early intervention programs in secondary schools [PDF]

open access: yes, 2004
Recent epidemiological studies in Australia have found that adolescent mental health issues are an important public health problem (Sawyer et al., 2001). These problems are often manifested in the classroom.
Campbell, Marilyn A.
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Hazards identification for safety and risk evaluation of hydroelectric dam power generation plant / Ali Mohammad Saedi [PDF]

open access: yes, 2013
There are many formal techniques for the systematic analysis of occupational safety and health in general as well as specific areas. Currently there is increased interest in the evaluation of environmental safety and health.
Saedi, Ali Mohammad
core  

A review of literature and computer models on exposure assessment [PDF]

open access: yes, 2009
At the present time, risk analysis is an effective management tool used by environmental managers to protect the environment from inevitable anthropogenic activities.
Oduyemi, K. O. K.   +11 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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