Results 41 to 50 of about 6,218,168 (337)
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Measuring the systemic risk in the South African banking sector
South African Journal of Economic and Management Sciences, 2017 Background: In the aftermath of the sub-prime crisis, systemic risk has become a greater priority for regulators, with the National Treasury (2011) stating that regulators should proactively monitor changes in systemic risk.
Gregory M. Foggitt +3 more
doaj +1 more source
Risk management under Omega measure [PDF]
, 2017 We prove that the Omega measure, which considers all moments when assessing portfolio performance, is equivalent to the widely used Sharpe ratio under jointly elliptic distributions of returns. Portfolio optimization of the Sharpe ratio is then explored,
Metel, Michael R. +2 more
core +2 more sources
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Acta Biomedica Scientifica, 2022 Relevance. Thyroid diseases in children and adolescents rank first in the structure of endocrine pathology. An issue related to comparability of data on prevalence obtained with different procedures is vital given the necessity to intensify activities ...
I. E. Shtina +4 more
doaj +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Analiz Riska Zdorovʹû, 2018 A precise, selective, and sufficiently sensitive quantitative procedure for determining chemicals contents in environmental objects and a human body is often a key to correct health risk assessment.
T.S. Ulanova +3 more
doaj +1 more source
Risk Management for Nonprofits [PDF]
, 2016 Our research, based on the first comprehensive financial analysis of New York's nonprofit sector, found that 10% of the city's nonprofits were insolvent and 40% had virtually no cash reserves. Less than 30% were financially strong.
Daniel Millenson +3 more
core
Framework for risk management software system for SMEs in the engineering construction sector [PDF]
, 2017 Small and medium-sized enterprises (SMEs) in construction sector are vulnerable and face exposure to risks whilst operating without risk management system in place.
Jannadi +5 more
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source