Results 101 to 110 of about 7,974,169 (304)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Influence of Snow Redistribution and Melt Pond Schemes on Simulated Sea Ice Thickness During the MOSAiC Expedition

Journal of Marine Science and Engineering
The observations of atmospheric, oceanic, and sea ice data from the Multidisciplinary drifting Observatory for the Study of Arctic Climate (MOSAiC) expedition were used to analyze the influence of snow redistribution and melt-pond processes on the ...
Jiawei Zhao, Yang Lu, Haibo Zhao, Xiaochun Wang, Jiping Liu   +4 more
doaj   +1 more source

Risk Prediction for Individuals [PDF]

JAMA, 2015
Van Calster, Ben, Steyerberg, Ewout W., Harrell, Frank H.   +2 more
openaire   +2 more sources

Risk prediction score plot.

, 2019
Risk prediction score plot.
Siobhan P. Brown (6861677), Evangelyn Nkwopara (5779505), Eric D. McCollum (252799), Tisungane Mvalo (5779511), Amy Sarah Ginsburg (814730), Susanne May (168728)   +5 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

DevRickybeats/Bankruptcy-Risk-Assessment: BANKRUPTCY RISK ASSESSMENT: A MACHINE LEARNING APPROACH TO BANKRUPTCY PREDICTION

<p>BANKRUPTCY RISK ASSESSMENT: A MACHINE LEARNING APPROACH TO BANKRUPTCY PREDICTION</p ...
IGWE RICKSON IKENNA
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Predicting tuberculosis risk [PDF]

The Lancet, 2016
Kik, Sandra V., Cobelens, Frank, Moore, David   +2 more
openaire   +3 more sources

Clinical Risk Score for Prediction of Urgency in Carotid Cavernous Sinus Fistulas

, 2023
Pawasoot Supasai, Kanwasee Kanjana, Yosanan Yospaiboon KKU Eye Center, Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandCorrespondence: Yosanan Yospaiboon, KKU Eye Center, Department of Ophthalmology, Faculty of ...
Supasai P, Kanjana K, Yospaiboon Y
core