Results 101 to 110 of about 7,559,776 (293)

Polygenic Risk Scores: Genomes to Risk Prediction

open access: yesClinical Chemistry, 2023
Tristan J Hayeck   +5 more
openaire   +3 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Analysis of Risk Factors and Risk Prediction for Cervical Lymph Node Metastasis in Thyroid Papillary Carcinoma [PDF]

open access: yes
Dandan Tian,1 Xiaoqin Li,1 Zhongzhi Jia2 1Department of Ultrasound, The Affiliated Changzhou No. 2 People’s Hospital of Nanjing Medical University, Changzhou, Jiangsu, 213164, People’s Republic of China; 2Department of Interventional Vascular, The ...
Li X, Tian D, Jia Z
core  

Low Cross‐Product Agreement in Global Coastal Marine Heatwaves (1982–2023) and Implications for Trend Attribution

open access: yesGeophysical Research Letters
Coastal marine heatwaves (MHWs) derived from satellite and blended sea surface temperature (SST) products often disagree, but the magnitude and drivers of this uncertainty remain poorly quantified.
Wenjin Sun   +4 more
doaj   +1 more source

An integrated evaluation for SWOT KaRIn Level-2 significant wave height product

open access: yesGIScience & Remote Sensing
Significant wave height (SWH) is a crucial parameter for studying ocean wave fields. Conventional nadir altimeters provide global SWH records via along-track sampling, yet their limited effective resolution constrains the capture of small-scale wave ...
Hang Xie   +4 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Risk Prediction Models for Gastric Cancer: A Scoping Review [PDF]

open access: yes
Linyu Xu, Jianxia Lyu, Xutong Zheng, Aiping Wang Department of Public Service, The First Affiliated Hospital of China Medical University, Shenyang, 110001, People’s Republic of ChinaCorrespondence: Aiping Wang, Department of Public Service, The First ...
Xu L, Zheng X, Wang A, Lyu J
core  

Statistical Downscaling of Future Temperature in Tianshan Mountains Based on Batch Gradient Descent Nonlinear Regression

open access: yesEarth and Space Science
Temperature is a key variable in alpine regions such as the Tianshan Mountains, which affects the population and economic development in lowlands by regulating the melting of snow and glaciers.
Wen‐Jie Zhang   +5 more
doaj   +1 more source

Suppression of Parasitic Peaks on CFOSAT SWIM Wave Spectra Based on a Specific Parametric Method

open access: yesRemote Sensing
Parasitic peaks are observed in the low wavenumber regions of Surface Waves Investigation and Monitoring (SWIM) wave height spectra. They can be attributed to random fluctuations in the wave spectra caused mainly by speckle noise, compromising the ...
Jingwei Gu   +5 more
doaj   +1 more source

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