Results 91 to 100 of about 7,559,776 (293)

General practitioners’ use of risk prediction tools and their application to Barrett’s oesophagus: a qualitative study [PDF]

, 2018
Background: Risk prediction tools are widely used for the early identification of disease and expediting referrals to medical specialists for further assessment.
Laws, TAC, Ireland, CJ, Gordon, Andrea L., Esterman, Adrian, Gordon, AL, Thompson, Sarah K., Ireland, Colin J., Laws, Tom A., Thompson, SK, Esterman, A   +9 more
core   +1 more source

Dynamic Assessment of Population Exposure to Urban Flooding Considering Building Characteristics

Land
Under intensifying climate change impacts, accurate quantification of population exposure to urban flooding has become an imperative component of risk mitigation strategies, particularly when considering the dynamic nature of human mobility patterns ...
Shaonan Zhu, Xin Yang, Jiabao Yang, Jun Zhang, Qiang Dai, Zhenzhen Liu   +5 more
doaj   +1 more source

Risk Prediction for Individuals [PDF]

JAMA, 2015
Van Calster, Ben, Steyerberg, Ewout W., Harrell, Frank H.   +2 more
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Predicting tuberculosis risk [PDF]

The Lancet, 2016
Kik, Sandra V., Cobelens, Frank, Moore, David   +2 more
openaire   +3 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

AI-Enabled conditional nonlinear optimal perturbation enhances ensemble prediction of extreme El Niño events

npj Climate and Atmospheric Science
Data-driven deep learning (DL) models often underestimate the intensity of extreme weather and climate events due to the scarcity of extreme samples in training datasets and the smoothing effects of gradient-based optimization.
Lu Zhou, Rong-Hua Zhang, Lingjiang Tao
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Identification and Forecasting of Typical Wind Shear and Shear Line Based on Two‐Dimensional Wind Field

Meteorological Applications
The forecasting of clear‐air wind shear presents a significant challenge in aviation meteorology. To improve the accuracy of wind shear identification and forecasting using coherent Doppler wind lidar, this study proposes an advanced method for ...
Anning Chen, Jinlong Yuan, Shuo Zhang, Yue Liu, Jiadong Hu, Jiawei Qiu, Haiyun Xia   +6 more
doaj   +1 more source