Results 91 to 100 of about 9,368,536 (289)

Summarising the seismic risk reduction processes in standard residential buildings of Yerevan: why don't we have real results?

Budownictwo i Architektura
The article addresses issues of ensuring housing safety. The aim of this work is to summarise the tasks set by the state for seismic risk reduction in Yerevan and to identify their reflection in the process of increasing the seismic resistance of ...
Karen Azatyan, Karen Rashidyants, Anush Ohanyan   +2 more
doaj   +1 more source

Towards improved public awareness for climate related disaster risk reduction in South Africa: A Participatory Development Communication perspective

Jàmbá, 2009
Southern Africa has frequently been struck by damaging climate hazards which increasingly continue to threaten sustainable development efforts. Ominously, climate models predict that the incidence of major ‘wet’ events, such as floods and cyclones will ...
Tigere Chagutah
doaj   +1 more source

A review of therapeutic options for managing the metabolic aspects of polycystic ovary syndrome

Therapeutic Advances in Endocrinology and Metabolism, 2020
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age. Metabolic sequelae associated with PCOS range from insulin resistance to type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD).
Mohammed Altigani Abdalla, Harshal Deshmukh, Stephen Atkin, Thozhukat Sathyapalan   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Understanding the Role of Remittances in Reducing Earthquake Risk [PDF]

, 2014
A report for the Humanitarian Innovation FundWith support from the Humanitarian Innovation Fund, a programme managed by ELRHA, the Earthquake risk and remittances research project from Practical Action and the Nepal Risk Reduction Consortium (NRRC) began
Dinanath Bhandari, Daniel Trusilo, Gehendra Gurung, Moira Reddick, Giovanni Congi, Bikram Manandhar   +5 more
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Community Perspective on Policy Options for Resettlement Management: A Case Study of Risk Reduction in Bududa, Eastern Uganda

PLoS Currents, 2018
Despite existing policy actions on Disaster Risk Reduction (DRR), many community members in Bududa still continue to settle in high-risk areas re-zoned for nonsettlement. There seems to be an apparent information asymmetry on expectations between the community and Government.
Neema, Stella, Mongo Bua, Grace, Tuhebwe, Doreen, Ssentongo, Julius, Tumuhamye, Nathan, Mayega, Roy William, Fishkin, James, Atuyambe, Lynn M, Bazeyo, William   +8 more
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Social vulnerability and disaster risk reduction needs: perspectives of women [PDF]

Integration of disaster risk reduction needs and experiences of different groups in the community with the built environment is significant to achieve disaster resilience.
Ginige, K. N., Amaratunga, Dilanthi, Haigh, Richard   +2 more
core   +3 more sources