Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Outcome of the public consultation on the draft Scientific Opinion on the risk of Phyllosticta citricarpa (Guignardia citricarpa) for the EU territory with identification and evaluation of risk reduction options [PDF]
, 2014 European Food Safety Authority (EFSA)
openalex +1 more source
Pride of the South: Risk Analysis for Marine Biosecurity in Fiordland [PDF]
This paper describes a model used to assess alternative scenarios for managing the marine biosecurity risk to Fiordland from vessel traffic. Scenarios are assessed in terms of risk reduction per dollar spent.
Piola, Richard +2 more
core +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Unilateral climate policy and competitiveness: The implications of differential emission pricing [PDF]
Unilateral emission reduction commitments raise concerns on international competitiveness and emission leakage that result in preferential regulatory treatment of domestic energy-intensive and trade-exposed industries.
Christoph Böhringer +1 more
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Threats to soil quality in Denmark - A review of existing knowledge in the context of the EU Soil Thematic Strategy [PDF]
, 2009 The EU Commission is preparing a proposal for a Soil Framework Directive with the purpose of protecting the soil resources in Europe. The proposal identifies six major threats to the sustained quality of soils in Europe. This report addresses the threats
Christensen, B.T. +2 more
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
STRATEGIES FOR USE OF TAX CLAIMS TRANSFER DURING ECONOMIC CRISIS [PDF]
Although the provisions of the Code of Fiscal Procedure give the image of some norms that must be observed word by word, behind the legislative text there are hidden a series of options which can be taken, or some optimal strategies.The identification of
Adrian Vintilescu Belciug +1 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Evidence-based management options for women at increased breast/ovarian cancer risk [PDF]
, 2017 Recent developments in our ability to predict breast cancer risk necessitates primary care physicians learn to evaluate breast cancer risk and its importance in shaping decisions concerning surveillance and risk reduction measures.
Bolliger, B. +3 more
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