Results 81 to 90 of about 1,380,859 (329)
Risk Communication and Prostate Cancer
The format in which risk is communicated influences how patients make health care decisions. The same statistical information may be summarized differently according to relative risk reduction, absolute risk reduction, number needed to treat, or odds ...
Dragan Ilic PhD +2 more
doaj +1 more source
Robustly Hedging Variable Annuities with Guarantees Under Jump and Volatility Risks [PDF]
Accurately quantifying and robustly hedging options embedded in the guarantees of variable annuities is a crucial task for insurance companies in preventing excessive liabilities.
Coleman, Thomas +3 more
core
Reducing urban heat wave risk in the 21st century [PDF]
Global warming increases the frequency, intensity and duration of heat waves, particularly endangering urban populations. However, the health risks of heat waves are distributed unequally between people because of intrinsic person-specific ...
Creutzig, Felix, Fernandez Milan, Blanca
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Background Chemoprevention is one of several methods that have been developed to help high-risk women reduce their risk of breast cancer. Reasons for the low uptake of chemoprevention are poorly understood. This paper seeks a deeper understanding of this
Tasleem J. Padamsee +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Surface water flood risk and management strategies for London: an agent-based model approach [PDF]
Flooding is recognised as one of the most common and costliest natural disasters in England. Flooding in urban areas during heavy rainfall is known as ‘surface water flooding’, considered to be the most likely cause of flood events and one of the ...
Crick, Florence +3 more
core +4 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
OPTIMAL CROP INSURANCE OPTIONS FOR ALABAMA COTTON-PEANUT PRODUCERS: A TARGET-MOTAD ANALYSIS [PDF]
Target-MOTAD was used to determine the optimal crop insurance options for two representative cotton and peanut farms in southern Alabama. Results showed that, for one of the farms, no crop insurance option was risk reducing given the yield history.
Duffy, Patricia A. +2 more
core +1 more source
IFE Plant Technology Overview and contribution to HiPER proposal
HiPER is the European Project for Laser Fusion that has been able to join 26 institutions and signed under formal government agreement by 6 countries inside the ESFRI Program of the European Union (EU). The project is already extended by EU for two years
Alvarez Ruiz, Jesus +19 more
core +1 more source

