Results 41 to 50 of about 11,478,693 (361)
Bone Marrow Transplantation, 2011 The European Group for Blood and Marrow Transplantation (EBMT) risk score provides a simple tool to assess instantly chances and risks of hematopoietic SCT(HSCT) for an individual patient pre-transplant. Five factors, age of the patient, stage of the disease, time from diagnosis, donor type and donor recipient gender combination augment risk for an ...
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Communicating Risk—Coronary Risk Scores
Journal of the Royal Statistical Society Series A: Statistics in Society, 2003 SummaryCardiovascular disease, particularly heart attack and stroke, is the major cause of death in adults in Europe. The underlying atherosclerosis which causes cardiovascular disease is difficult to treat or reverse, and this has led to intense interest in strategies to prevent its development.
Ian M. Graham, Elizabeth Clavel
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Quantifying the risk of coronary artery disease in a community: The Bambuí Project [PDF]
Arquivos Brasileiros de Cardiologia, 2003 OBJECTIVE: To determine the coronary risk profile in adults and elderly in a community. METHODS: The study comprised a sample of adults (30-59 years, n=547) and the entire elderly population (60-74 years, n=1165) residing in Bambuí town, Brazil.
Sandhi Maria Barreto +3 more
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Genomics and Prognosis Analysis of N6-Methyladenosine Regulators in Lung Adenocarcinoma
Frontiers in Genetics, 2021 Objective: N6-methyladenosine (m6A) modification is involved in modulating various biological processes in human cancers. But the implication of m6A modification in lung adenocarcinoma (LUAD) is still unclear.
Yanpin Ma, Huping Zhang
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Identification and Validation of Immune-Related LncRNA Prognostic Signature for Lung Adenocarcinoma
Frontiers in Genetics, 2021 This study aimed to establish a prognostic risk model for lung adenocarcinoma (LUAD). We firstly divided 535 LUAD samples in TCGA-LUAD into high-, medium-, and low-immune infiltration groups by consensus clustering analysis according to immunological ...
Guomin Wu +6 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar +8 more
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Learning Optimized Risk Scores
, 2016 Risk scores are simple classification models that let users make quick risk predictions by adding and subtracting a few small numbers. These models are widely used in medicine and criminal justice, but are difficult to learn from data because they need to be calibrated, sparse, use small integer coefficients, and obey application-specific operational ...
Ustun, Berk, Rudin, Cynthia
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JAMA Network Open, 2020 Key Points Question Are polygenic risk scores associated with changes in breast cancer risks for individuals with a pathogenic variant in moderate-risk breast cancer genes? Findings In this case-control study of 9802 women carrying pathogenic variants of
S. Gallagher +13 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small +3 more
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Communications BiologyPolygenic risk score (PRS) is useful for capturing an individual’s genetic susceptibility. However, previous studies have not fully exploited the potential of the risk factor PRS (RFPRS) for disease prediction.
Hyein Jung +6 more
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