Results 71 to 80 of about 11,478,693 (361)

A combined immune and exosome-related risk signature as prognostic biomakers in acute myeloid leukemia

Hematology
Objectives Acute myeloid leukemia (AML) is one of the common hematological diseases with low survival rates. Studies have highlighted the dysregulated expression of immune-related and exosome-related genes (ERGs) in cancers.
Zenghui Fang, Jiali Fu, Xin Chen
doaj   +1 more source

Cross-talk of four types of RNA modification proteins with adenosine reveals the landscape of multivariate prognostic patterns in breast cancer

Frontiers in Genetics, 2022
Background: Breast cancer (BC) is the most common malignant tumour, and its heterogeneity is one of its major characteristics. N6-methyladenosine (m6A), N1-methyladenosine (m1A), alternative polyadenylation (APA), and adenosine-to-inosine (A-to-I) RNA ...
Xuliren Wang, Fangdie Ye, Min Xiong, Bingqiu Xiu, Weiru Chi, Qi Zhang, Jingyan Xue, Ming Chen, Liyi Zhang, Jiong Wu, Jiong Wu, Yayun Chi   +11 more
doaj   +1 more source

Prostate cancer risk prediction using a polygenic risk score

Scientific Reports, 2020
Hereditary factors have a strong influence on prostate cancer (PC) risk and poorer outcomes, thus stratification by genetic factors addresses a critical need for targeted PC screening and risk-adapted follow-up.
C. Sipeky, K. Talala, T. Tammela, K. Taari, A. Auvinen, J. Schleutker   +5 more
semanticscholar   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score

Circulation, 2019
Supplemental Digital Content is available in the text. Background: The ability of a genetic risk score to predict risk in established cardiovascular disease and identify individuals who derive greater benefit from PCSK9 (proprotein convertase subtilisin ...
N. Marston, Frederick K. Kamanu, F. Nordio, Yared Gurmu, C. Roselli, P. Sever, T. Pedersen, A. Keech, Huei Wang, Armando Lira Pineda, R. Giugliano, S. Lubitz, P. Ellinor, M. Sabatine, C. Ruff   +14 more
semanticscholar   +1 more source

Psychological Safety Among Interprofessional Pediatric Oncology Teams in Germany: A Nationwide Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn, Anna‐Lena Herbach, Christian Bock, Katharina Fleig, Urs Mücke   +4 more
wiley   +1 more source

High -density lipoprotein cholesterol as a predictor for diabetes mellitus

Caspian Journal of Internal Medicine, 2018
Background: Diabetes is a prevalent chronic disease around the world. To evaluate risk of diabetes comprehensively, we developed a score model for the risk prediction with HDL-C as a protective factor.
Hong Wu, Peng Ouyang, Wenjun Sun
doaj  

Cross-organ hierarchy of HLA molecular mismatches in donor-specific antibody development in solid organ transplantations

Cell Reports Medicine
Summary: Donor-specific antibodies (DSAs) against human leukocyte antigen (HLA) play a crucial role in antibody-mediated rejection, a major barrier to successful organ transplantation.
Masaaki Hirata, Kazuto Tsukita, Takero Shindo, Shintaro Yagi, Takashi Ito, Satona Tanaka, Ryo Fujimoto, Hidenao Kayawake, Kenji Nakamura, Nobuhiro Fujiyama, Mitsuru Saito, Kimiko Yurugi, Rie Hishida, Arisa Kato, Atsushi Kawaguchi, Tomonori Habuchi, Takashi Kobayashi, Hiroshi Date, Etsuro Hatano   +18 more
doaj   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

A scoring model based on bacterial lipopolysaccharide-related genes to predict prognosis in NSCLC

Frontiers in Genetics
BackgroundNon-small cell lung cancer (NSCLC) has high incidence and mortality rates. The discovery of an effective biomarker for predicting prognosis and treatment response in patients with NSCLC is of great significance.
Nandi Bao, Xinxin Zhang, Chenyu Lin, Feng Qiu, Guoxin Mo   +4 more
doaj   +1 more source