Results 91 to 100 of about 579,201 (262)
Revista Colombiana de Estadística, 2004 This paper presents some general concepts in risk theory, and especially in credit risk, where statistics plays a central role. The text emphasizes on decision trees as a very usefull tool in the calculus of probabilities related to credit risk.En este ...
Cardona Hernández Paola Andrea
doaj
Credit Risk: Structural Models With Risk-Neutral Approach Under Uncertainty Theory
Journal of MathematicsCredit risk, a critical component of financial risk management, concerns the possibility of borrower default. Traditional structural models, such as Merton’s framework, assume that firm asset values evolve according to stochastic differential equations ...
Muhammad Shoaib Khan +2 more
doaj +1 more source
The Moderating Role of Risk Committee on the Corporate Risk Disclosure-Firm Value Relationship
Jurnal Dinamika Akuntansi dan BisnisThis study examines the relationship between Corporate Risk Disclosure (CRD) and firm value (MVA), with the Risk Committee as a moderating variable. Using a sample of 182 manufacturing companies listed on the Indonesia Stock Exchange (IDX) during 2020 ...
Lydia Ulimazni Vivolanda +2 more
doaj +1 more source
Solving the Single-Vehicle Self-Driving Car Trolley Problem Using Risk Theory and Vehicle Dynamics. [PDF]
Sci Eng Ethics, 2020 Davnall R.
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The evolution of uncertainty or development of economic perception for the risk [PDF]
Икономика и компютърни науки, 2017 Risk is one of the main categories in а modern life. The research of its nature requires study of historical background of the category. The article presents dynamic of the understandings for risk in the economic theory.
Galin Markov
doaj
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source