Results 61 to 70 of about 542,647 (304)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Automating fault tolerance in high-performance computational biological jobs using multi-agent approaches [PDF]
, 2014 Background: Large-scale biological jobs on high-performance computing systems require manual intervention if one or more computing cores on which they execute fail.
Varghese, Blesson +2 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Determinants of Risk Tolerance [PDF]
International Journal of Economics, Finance and Management Sciences, 2014 Risk aversion is an important factor in explaining many everyday decisions. Thus, one asks which determinants can explain different attitudes towards risk. Several studies show different risk attitudes with respect to gender, age, income, and wealth (e.g. [19]).
openaire +1 more source
ON THE LINKAGE BETWEEN FINANCIAL RISK TOLERANCE AND RISK AVERSION [PDF]
Journal of Financial Research, 2008 AbstractWe explore the linkage between financial risk tolerance (FRT) and risk aversion. To do this, we obtain FRT scores from a psychometrically validated survey and conduct a battery of online lottery choice experiments involving the same nonstudent participants.
Faff, Robert (R18017) +2 more
openaire +5 more sources
Journal of Business & Banking, 2016 Nowadays, the economy has been growing so rapidly that it makes people think of get-ting their income beyond the salary they get from their work. One way to get it is by investing. However, when investing, they find a few things to note such as financial
I Putu Santika Putra +4 more
doaj +1 more source
Heterogeneity in Risk-Taking During the COVID-19 Pandemic: Evidence From the UK Lockdown
Frontiers in Psychology, 2021 In two pre-registered online studies during the COVID-19 pandemic and the early 2020 lockdown (one of which with a UK representative sample) we elicit risk-tolerance for 1,254 UK residents using four of the most widely applied risk-taking tasks in ...
Benno Guenther +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source