Clozapine as add-on medication in the maintenance treatment of bipolar and schizoaffective disorders - A case series [PDF]
, 2002 Atypical neuroleptics are increasingly used in the treatment of bipolar and schizoaffective disorders. Currently, numerous controlled short-term studies are available for clozapine, olanzapine, risperidone or quetiapine, but long-term data are still ...
Amann, B. +5 more
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Effect of Formulation Variables on Fabrication of Risperidone Loaded Nanoparticles for Sustained Drug Delivery [PDF]
, 2022 Dipti Gohil +2 more
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Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials
British Journal of Pharmacology, EarlyView.Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen +2 more
wiley +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2019 Risperidone is an atypical antipsychotic acting mainly as a dopamine D2 and serotonin 5-HT2 receptors antagonist prescribed in the treatment of schizophrenia and various affective disorders. Risperidone has been reported to be associated with weight gain,
Rehmat Shah +3 more
doaj +1 more source
Effect of CYP2D6 polymorphisms on plasma concentration and therapeutic effect of risperidone
BMC Psychiatry, 2021 Background This study aimed to investigate the influence of CYP2D6 polymorphisms on risperidone plasma concentrations in patients with schizophrenia. Based on pharmacogenomics, we examined whether plasma concentration of risperidone is associated with ...
Jinjun Lu +11 more
doaj +1 more source
Risperidone Treatment of Autistic Disorder: Longer-Term Benefits and Blinded Discontinuation After 6 Months [PDF]
, 2005 Objective: Risperidone is effective for short-term treatment of aggression, temper outbursts, and self-injurious behavior in children with autism. Because these behaviors may be chronic, there is a need to establish the efficacy and safety of longer-term
Aman, Michael G. +30 more
core +1 more source
Caregivers' perspectives of support needs for adolescents with fetal alcohol spectrum disorder
Children &Society, EarlyView.Abstract Research focused on fetal alcohol spectrum disorder (FASD) is often deficit‐focused, limiting a holistic understanding of individuals' support needs. Families of adolescents with FASD also struggle to access appropriate services. Using semi‐structured interviews, the current study explored the perspectives of seven caregivers of adolescents ...
Kelly Skorka +4 more
wiley +1 more source
Are specific initiatives required to enhance prescribing of generic atypical antipsychotics in Scotland? International implications [PDF]
, 2013 Background National and regional authorities in Scotland have introduced multiple measures to appreciably enhance prescribing efficiency for the proton pump inhibitors (PPIs), statins and renin-angiotensin inhibitor drugs.
Alessi-Severini +82 more
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Psychiatry and Clinical Psychopharmacology, 2019 Risperidone, which is one of the most commonly prescribed second-generation antipsychotics can cause several sexual adverse effects. To date, research on the sexual side effects of risperidone has been mostly restricted to symptoms of decreased libido ...
Mohammadreza Shalbafan +2 more
doaj +1 more source
Low-Dose Risperidone-Induced Facial Edema in a Child with Conduct Disorder
Psychiatry and Behavioral Sciences, 2018 Risperidone, a benzisoxazole derivate, is a widely prescribed antipsychotic agent that binds with high affinity to dopamine D2, serotonin type 2 (5-HT2) and α1-adrenergic receptors, and causes antagonism at these receptor sites. Although risperidone
Hamza Ayaydin, Sermin Bilgen Ulgar
doaj +1 more source