Results 131 to 140 of about 10,571 (188)
Validation of a Gastric-Juice-Analysis-Based Approach to <i>H. pylori</i> Diagnosis. [PDF]
Diagnostics (Basel)Pigò F, Fernicola GC, Lupo M, Ceraso C, Esposito L, Bertani H, Grande G, Cocca S, Russo S, Marocchi M, Marsico M, Boarino V, Casciola R, Conigliaro R. +13 moreeuropepmc +1 more sourceAutosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production
Allergy, EarlyView.IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.Giorgia Moschetti, Chiara Vasco, Francesca Clemente, Paola Larghi, Sara Maioli, Edoardo Scarpa, Elena Carelli, Nadia Pulvirenti, Maria Lucia Sarnicola, Mariacristina Crosti, Manal Bel Imam, Willem van de Veen, Loris Rizzello, Sergio Abrignani, Lucia A. Baselli, Rosa Maria Dellepiane, Maria Carrabba, Giovanna Fabio, Jens Geginat +18 morewiley +1 more sourceUse of Aztreonam-avibactam for infections caused by MBL-producing <i>Enterobacterales</i>. [PDF]
New Microbes New InfectMedioli F, Bavaro DF, Cento V, Scuderi C, Tordato F, Casana M, Diella L, Cilli A, Morelli P, Varisco B, Della Porta MG, Carlo-Stella C, Vanoni M, Costantini E, Bramanti S, Cecconi M, Bussini L, Bartoletti M. +17 moreeuropepmc +1 more sourceMolecular Characterization of Non‐Specific Esophagitis Reveals a Distinct Non‐Eosinophilic Phenotype With Fibrotic Traits
Allergy, EarlyView.This study comprehensively characterizes non‐specific esophagitis and elucidates eosinophil‐independent fibrosis mechanisms. NSE appears to be a distinct fibrotic phenotype of the esophagus, without any considerable overlap with GERD and other chronic inflammatory disorders such as EoE or lymphocytic esophagitis.Marc Pfefferle, Darko Stojkov, Dagmar Simon, Emilie Gueguen, Marcin Wawrzyniak, Margaret H. Collins, Mirna Chehade, Evan S. Dellon, Glenn T. Furuta, Ikuo Hirano, Nirmala Gonsalves, Fouad J. Moawad, Luc Biedermann, Alain M. Schoepfer, Alex Straumann, Hans‐Uwe Simon, Thomas Greuter +16 morewiley +1 more sourceTreatment Dose Increase Versus Co‐Medication in Allergic Rhinitis: Systematic Review With Dose–Response Network Meta‐Analysis
Allergy, EarlyView.ABSTRACT Background
To achieve adequate symptom control, patients with allergic rhinitis (AR) often need to increase their medication dose or add other treatments (co‐medication). We aimed to perform a systematic review to compare the efficacy and safety of AR medications for increased dose versus co‐medication.Bernardo Sousa‐Pinto, Rafael José Vieira, Sara Gil‐Mata, Ana Margarida Pereira, Vítor Henrique Duarte, Antonio Bognanni, Manuel Marques‐Cruz, Paweł Jemioło, Mattia Giovannini, Danilo di Bona, Arnav Agarwal, Mark S. Dykewicz, Mohamed H. Shamji, Maria Jose Torres, Torsten Zuberbier, Ludger Klimek, Alexandro W. L. Chu, Holger J. Schünemann, Guido Schwarzer, João A. Fonseca, Jean Bousquet, on behalf of the ARIA 2024–2025 systematic reviews group, Ana Teixeira‐Ferreira, André Ferreira, António Cardoso‐Fernandes, Despo Ierodiakonou, Diana Portela, Ewa Borowiack, Ewelina Sadowska, Henrique Ferreira‐Cardoso, Hugo Viegas, Izabel Pera Calvi, João Castro‐Teles, José Laerte Boechat, Juliana Pereira‐Macedo, Maria Inês Torres, Marta Soares Pereira, Miguel Campos‐Lopes, Nuno Lourenço‐Silva, Pau Riera‐Serra, Paula Perestrelo, Raquel Albuquerque‐Costa, Renato Ferreira‐da‐Silva, Rita A. Silva Ribeiro, Tuuli Thomander +44 morewiley +1 more sourceRoute of Allergen Immunotherapy: A Global Look Into Physicians' Motivations
Allergy, EarlyView.Little is known about the factors driving AIT prescription in clinical practice, including the level of personalization from patient to patient. Patient‐centred factors theoretically would favour SLIT prescription. Doctors’ knowledge, training, and country influence the final decision on the route.Carmen Vidal, Davide P. Caimmi, Pablo Rodriguez del Rio, Óscar Lado‐Baleato, Francisco Gude, Pilar Rico‐Nieto, Thomas B. Casale, Jorge A. Aguilar, Maryam Ali Al‐Nesf, Fatima Ashkanani, Adeeb Bulkhi, Juan C. Cardet, Claudia Almendarez, Silvia Caimmi, Iván Cherrez, Enza D’Auria, Stephanie Dramburg, Motohiro Ebisawa, Naoko Fusayasu, Maximiliano Gomez, Sandra Gonzalez‐Diaz, Carla Irani, Andrey Kamaev, Connie Katelaris, Narinder Kaur, Oksana KurBacheva, José I. Larco, Désirée Larenas‐Linnemann, Margaret Li, Olga Patricia Monge‐Ortega, Pablo Moreno, Oliver Pfaar, Cesar F. Pozo‐Beltrán, Marta E. Rubio, Jorge Sanchez, Giovanni Sedo, Silvia Uriarte, Lin Yang, Hao Chen, Rongfei Zhu, Pascal Demoly, Moises A. Calderon, on behalf of the CHOICE‐Global Survey Team +42 morewiley +1 more sourceSperm Selection Using Micro Swim‐Up: Improvement of Chromatin Integrity Compared to Density Gradient Centrifugation
Andrology, EarlyView.ABSTRACT Background
Selecting high‐quality spermatozoa with optimal nuclear integrity is a crucial step in assisted reproductive technologies (ART). While density gradient centrifugation (DGC) is widely used, the associated centrifugation steps may induce cell stress, potentially damaging sperm DNA.Simone Palini, Serena Benedetti, Silvia De Stefani, Luca Galluzzi, Mariangela Primiterra, Sara Rita D'Errico, Michele Tanturli, Monica Muratori +7 morewiley +1 more sourceReality of Osteoporosis in Primary Healthcare: An Observational Study in a Portuguese Local Health Unit. [PDF]
CureusPinto N, Machado A, Matos A, Cardoso CS, Martins Figueiredo J, Silveira JC, De Oliveira E Silva J, Gonçalves D, Valente P, Lourenço MH, Fonseca R. +10 moreeuropepmc +1 more source
