Results 121 to 130 of about 53,318 (258)

In Vivo pharmacokinetic interactions of ribociclib with rivaroxaban and apixaban in rats: implications for increased drug exposure and dose adjustments

Frontiers in Pharmacology
BackgroundApixaban (API) and rivaroxaban (RIVA) are orally available inhibitors of coagulation factor Xa and are commonly used to treat cancer-related venous thrombosis.
Zihan Liu, Zihan Liu, Wenyu Du, Wenyu Du, Qimin Wang, Zhi Wang, Jing An, Yinling Ma, Zhanjun Dong, Ying Li   +9 more
doaj   +1 more source

Cancer-Associated Thrombosis in Cirrhotic Patients with Hepatocellular Carcinoma. [PDF]

, 2018
It is common knowledge that cancer patients are more prone to develop venous thromboembolic complications (VTE). It is therefore not surprising that patients with hepatocellular carcinoma (HCC) present with a significant risk of VTE, with the portal vein
Burra, P, Campello, E, Russo, Fp., Simioni, P, Spiezia, L, Zanetto, A   +5 more
core   +1 more source

Multi‐Chamber Intracardiac Thrombi Complicated With Pulmonary and Lower Extremity Thrombosis in Male Patient: Case Report and Literature Reviews

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Multi‐chamber intracardiac thrombi are a rare and high‐risk complication in dilated cardiomyopathy, even during sinus rhythm. This case highlights the associated dangers of hemodynamic compromise and systemic embolization. Management requires vigilant anticoagulation and close monitoring to balance thromboembolic and bleeding risks.
Eba Fufa, Yitagesu Getachew, Samson Mulugeta, Abera Birhanu, Abel Yirga, Amdemeskel Mersha, Banchiaymolu Damtie, Balew Arega, Begashaw Belay, Brook Fanuel, Misgana Lukas   +10 more
wiley   +1 more source

Safety profile of rivaroxaban in first-time users treated for venous thromboembolism in four European countries.

PLoS ONE
BackgroundThe European rivaroxaban post-authorization safety study evaluated bleeding risk among patients initiated on rivaroxaban or vitamin K antagonists for the treatment and secondary prevention of venous thromboembolism in routine clinical practice ...
Ana Ruigómez, Tania Schink, Annemarie Voss, Ron M C Herings, Elisabeth Smits, Karin Swart-Polinder, Yanina Balabanova, Gunnar Brobert, Kiliana Suzart-Woischnik, Luis Alberto García Rodríguez   +9 more
doaj   +1 more source

Healthcare resource utilization and costs among nonvalvular atrial fibrillation patients initiating rivaroxaban or warfarin in skilled nursing facilities: a retrospective cohort study [PDF]

, 2019
Vishakha Mittal, Bingcao Wu, Ji Young Song, Dejan Milentijevic, Veronica Ashton, Dheeraj Mahajan   +5 more
openalex   +1 more source

Delayed Diagnosis of a Giant Abdominal Aortic Aneurysm Complicating to Aortoenteric Fistula: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT A 53‐year‐old man with chronic back pain and systemic symptoms was diagnosed with a massive abdominal aortic aneurysm (AAA) and aortoenteric fistula (AEF), which can cause severe gastrointestinal bleeding and potentially fatal side effects.
Ola Gamal Badawi Khalil, Mohammed Eltaieb Ali Mohammed, Salah Eldin Mohamed Elmustafa Hassan, Khalid Alshibli Dafalla Gasmalla, Rania Ahmed Elsiddig Hassan, Yousif Omer Elgaili Yousif   +5 more
wiley   +1 more source

Rivaroxaban alleviates hepatic sinusoidal obstruction syndrome in mice by modulating the gut microbiota and inhibiting the PI3K/Akt signaling pathway

Frontiers in Microbiology
IntroductionHepatic sinusoidal obstruction syndrome (HSOS) is a vascular liver disease with a high mortality rate, and treatment methods are limited. Rivaroxaban is an oral anticoagulant.
Wencheng Liu, Yanbin Cheng, Xue Han, Junlin Xia, Qingyu Wei, Bing Chang, Quansheng Li   +6 more
doaj   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 46-62, January 2026.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik, Ainhoa Gomez‐Lumbreras, Guilherme Del Fiol, Kensaku Kawamoto, Katy E. Trinkley, Thomas Reese, Aubrey Jones, Daniel C. Malone   +7 more
wiley   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 241-254, January 2026.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

PENGARUH PEMBERIAN RIVAROXABAN TERHADAP PENURUNAN INSIDENSI DEEP VEIN THROMBOSIS (DVT) PASCA OPERASI TOTAL KNEE REPLACEMENT (TKR) DI RSUD DR. ZAINOEL ABIDIN BANDA ACEH [PDF]

, 2017
Deep Vein Thrombosis (DVT) merupakan gumpalan darah (trombus) yang terbentuk pada vena didalam tubuh yang memungkinkan terjadinya gangguan sirkulasi dan memblokir aliran darah ke paru-paru serta dapat menyebabkan kerusakan permanen pada katup pembuluh ...
Dian Wathani
core