Results 31 to 40 of about 13,275 (183)

Current situation and issues regarding termination of risk management plans in Japan

Frontiers in Medicine
IntroductionIn Japan, drugs approved after the 2013 implementation of the risk management plan (RMP) have the opportunity to be evaluated for RMP termination. However, the guidelines for risk management following the termination of an RMP remain unclear.
Natsuko Kameyama, Aoi Hosaka, Hideki Maeda, Hideki Maeda   +3 more
doaj   +1 more source

Low awareness of risk mitigation prescribing in response to dual crises of COVID-19 and overdose deaths among people who use unregulated drugs in Vancouver, Canada

Harm Reduction Journal, 2022
Background When the novel coronavirus pandemic emerged in March 2020, many settings across Canada and the USA were already contending with an existing crisis of drug overdoses due to the toxic unregulated drug supply.
Mana Moshkforoush, Kora DeBeck, Rupinder Brar, Nadia Fairbairn, Zishan Cui, M.-J. Milloy, Jane Buxton, Tanis Oldenburger, Will McLellan, Perry Kendall, Kali Sedgemore, Dean Wilson, Thomas Kerr, Kanna Hayashi   +13 more
doaj   +1 more source

Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco, Troy D. Wood, Raymond Cha, Jill S. Hochreiter, Susan L. Rosenkranz, Mona Farhad, Kyle R. Whitson, Connor E. Gould, Lauren E. Hill, Linda L. Hale, Philip H. Lindhorst, Diala Ghazal, Charlene R. Taylor, Madiha Quraishi, Suzanne M. Siminski, Yoninah Cramer, Heather L. Sprenger, Gene D. Morse   +17 more
wiley   +1 more source

Mitigating unfavourable treatment outcomes and acquired rifampicin resistance in isoniazid-resistant tuberculosis: the role of fluoroquinolone

Journal of Microbiology, Immunology and Infection
Background: Rifampicin (RMP), ethambutol, and pyrazinamide (PZA) for 6–9 months were recommended for the management of isoniazid-resistant, rifampicin-susceptible tuberculosis (Hr-TB), but recommendations on fluoroquinolones (FQs) were inconsistent.
Pin-Hui Lee, Ching-Han Liu, Pei-Chun Chan, Ya-Chun Yang, Po-Wei Chu, Chi-Fang Feng, Hsiu-Yun Lo, Chia-Chi Lee, Chen-Yuan Chiang   +8 more
doaj   +1 more source

Mechanisms of Protective Effect of Ramulus Mori Polysaccharides on Renal Injury in High-Fat Diet/Streptozotocin-Induced Diabetic Rats

Cellular Physiology and Biochemistry, 2015
Background: Diabetic nephropathy (DN) is the most important complication of diabetes and the most common cause of end-stage renal disease (ESRD). Aims: A recent study established that the Ramulus mori polysaccharides (RMP) exert antioxidant effects on DN
Xi Li, Ling Wang, Xingxin Gao, Guoping Li, Honghua Cao, Dezhi Song, Shuangqi Cai, Tao Liang, Bo Zhang, Gang Du   +9 more
doaj   +1 more source

Robotic single-site versus multi-port myomectomy: a case–control study

BMC Surgery, 2021
Background This study aimed to evaluate the compatibility of robotic single-site (RSS) myomectomy in comparison with the conventional robotic multi-port (RMP) myomectomy to achieve successful surgical outcomes with reliability and reproducibility ...
So Hyun Ahn, Joo Hyun Park, Hye Rim Kim, SiHyun Cho, Myeongjee Lee, Seok Kyo Seo, Young Sik Choi, Byung Seok Lee   +7 more
doaj   +1 more source

Neighbors, Drought, and Nitrogen Application Affect the Root Morphological Plasticity of Dalbergia odorifera

Frontiers in Plant Science, 2021
In forest systems, neighbor-induced root morphological plasticity (RMP) is species specific and environment dependent. However, related studies on leguminous woody trees remain sparse.
Li-Shan Xiang, Li-Shan Xiang, Ling-Feng Miao, Ling-Feng Miao, Fan Yang, Fan Yang, Fan Yang   +6 more
doaj   +1 more source

Pancreatic Adenocarcinoma: Diagnosis by Ultrasound‐Guided Fine‐Needle Aspiration—Cyto‐Histological Correlation and Experience at a Multidisciplinary Tertiary Reference Center

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Pancreatic adenocarcinoma (PDAC) is characterized by its poor prognosis. Cytology is essential for diagnostic confirmation and ancillary studies. The endoscopic ultrasound (EUS) set a precedent, facilitating cytological sampling through fine‐needle aspiration (FNA), with a sensitivity of 93% and a specificity of 95%.
Judith González‐López, Mónica Elizabeth Bauza, Judith Pérez‐Rojas, Cecilia López‐Valdivia, Carlos Zac Romero, Óscar Castells‐Perona, Cristina Ballester‐Ibáñez, Eva Montalvá‐Orón, Rafael López‐Andújar, Lidia Argüello‐Viudez, Mireya Prieto Rodríguez   +10 more
wiley   +1 more source

No Charging but Protection: Lifetime Prolongation of Spontaneously‐polarized Electrets for Energy Harvesting Applications

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A bilayer protection approach is proposed for slowing down the surface potential decay of thin films of spontaneously‐polarized electret materials. The electret and the protective films are characterized, and the protection effectiveness is investigated under the effects of light illumination, water contact and mechanical impact.
Seyedali Sabzpoushan, Henry Juncker, Peter Woias   +2 more
wiley   +1 more source

Comparative cytogenetic study in Muscidae flies

Brazilian Journal of Biology
The chromosome modal number in Muscoidea Diptera is 2n = 12, including five pairs of autosomes and one sex chromosome pair. Nevertheless, some species with 2n = 10 chromosomes have been described, all of them from the Muscidae family.
PP. Parise-Maltempi, RMP. Avancini
doaj   +1 more source