Results 41 to 50 of about 18,612 (273)

A proposed research misconduct policy for universities and postgraduate colleges in developing countries

open access: yesNigerian Postgraduate Medical Journal, 2020
Research misconduct policy (RMP) is a legal document that shows the definitions of the various types of misconduct, describes the inquiry and investigation of allegations, and the appropriate penalties that should be imposed.
Adedoyin Adekunle Adesanya
doaj   +1 more source

Mortalidade por câncer em populações indígenas no Estado do Acre, Brasil

open access: yesCadernos de Saúde Pública, 2019
O objetivo do estudo foi estimar a mortalidade por câncer em povos indígenas no Estado do Acre, Brasil. Trata-se de estudo observacional descritivo, com base no banco nominal do SIM (Sistema de Informações sobre Mortalidade), referente ao período de 1º ...
Maria Fernanda de Sousa Oliveira Borges   +3 more
doaj   +1 more source

Exploring the subjective experience of rave party participants in Israel who consume psychedelic drugs: a qualitative inquiry

open access: yesHarm Reduction Journal, 2023
Background Rave music parties (RMP) are a world-wide socio-cultural phenomenon, where people listen to rave music while frequently consuming psychedelic drugs.
Yula Milshteyn, Moshe Bensimon
doaj   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan   +10 more
wiley   +1 more source

Construction procedure of pMD19▵rmp::Kan. [PDF]

open access: yes, 2014
After subcloning Rmp gene in pMD19-T, forward primer was designed in the 3′-flanking region, and reverse primer was designed in the 5′-flanking region. PCR was conducted to obtain DNA fragment pMD19▵rmp with flanking regions in both terminals, which was ...
Yanli Mao (530225)   +8 more
core   +1 more source

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

open access: yesAdvanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi   +9 more
wiley   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

open access: yesAdvanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li   +10 more
wiley   +1 more source

Schematic diagram of rmp mutant gene structure. [PDF]

open access: yes, 2014
Inactivated gene Δrmp::Kan was acquired by substituting the 261–460 nucleotide residues of rmp gene for kanamycin-resistant gene, which was then subcloned in pMD19-T vector, yielding pMD19Δrmp::Kan eventually.
Yanli Mao (530225)   +8 more
core   +1 more source

Current situation and issues regarding termination of risk management plans in Japan

open access: yesFrontiers in Medicine
IntroductionIn Japan, drugs approved after the 2013 implementation of the risk management plan (RMP) have the opportunity to be evaluated for RMP termination. However, the guidelines for risk management following the termination of an RMP remain unclear.
Natsuko Kameyama   +3 more
doaj   +1 more source

Robotic single-site versus multi-port myomectomy: a case–control study

open access: yesBMC Surgery, 2021
Background This study aimed to evaluate the compatibility of robotic single-site (RSS) myomectomy in comparison with the conventional robotic multi-port (RMP) myomectomy to achieve successful surgical outcomes with reliability and reproducibility ...
So Hyun Ahn   +7 more
doaj   +1 more source

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