Results 61 to 70 of about 20,565 (264)

Resistive Interchange Instability Response to External RMP, and its Parameter Dependence to Suppress the Instability

We derive an empirical scaling law for the external RMP (Resonant Magnetic Perturbation) amplitude required to completely suppress the resistive interchange MHD instabilities of m/n = 1/1 (m and n are the poloidal and toroidal mode numbers, respectively),
ITO, Shu, SAKAKIBARA, Satoru, WATANABE, Kiyomasa, TAKEMURA, Yuki   +3 more
core   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

Epilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta, Morgan Robinson, Zhefu Que, Zaiyang Zhang, Karen V. Salazar‐Salazar, Hope Elizabeth Harlow, Vinayak Shankar, Seoyeon Hong, Muhan Wang, Conrad M. Otterbacher, Hina Kadono, Manasi Halurkar, Harish Kothandaraman, Nadia Atallah Lanman, Trang Nguyen, Kyle Wettschurack, Benjamin Zirkle, Layan Yunis, Ningren Cui, Xiaoling Chen, Jingliang Zhang, Jiaxiang Wu, William C. Skarnes, Chongli Yuan, Feng Guo, Megan Abbott, Yang Yang   +26 more
wiley   +1 more source

A Nonparametric Approach to The Analysis of HACCP/RMP Implementation Process [PDF]

In this paper we conduct an analysis of the implementation of HACCP/RMP in the NZ Meat Industry based on the data collected from our recent survey. Nonparametric methods are used to measure the association between plant characteristics such as size, age,
Scrimgeour, Frank G., Cao, Kay
core  

Evidence for Anti-Fibrinolytic Activity of Red Cell-Derived Microparticles (RMP): A Novel Hemostatic Action of RMP

, 2016
BACKGROUND. RMP have been developed as novel hemostatic agents for treatment of bleeding disorders [Thromb Haemost 110:751,2013]. RMP generate thrombin in vitro through activation of contact pathway independent of tissue factor. They correct coagulopathy
Azad, Mazieyar, Bidot, Carlos J, Ahn, Yeon S, Gonzalez, Martha, Jy, Wenche, Horstman, Lawrence L   +5 more
core   +1 more source

β‐Hydroxybutyrate reduces neuronal excitability via GIRK channels

Epilepsia, EarlyView.
β‐Hydroxybutyrate decreases neuronal excitability by activating GIRK channels through HCAR2 signaling, providing a cellular mechanism that may contribute to the antiseizure effects of the ketogenic diet. Abstract Objective The ketogenic diet is used to treat drug‐resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure ...
Soudabeh Naderi, John Williamson, Jhanvi Patel, Samikksha Kumar, Huayu Sun, Lucy Dang Nguyen, Katarzyna Rękawek, Ifrah Zawar, Jaideep Kapur   +8 more
wiley   +1 more source

RMP Compliance [PDF]

, 2006
After the Clean Air Act Amendments became finalized in 1996, the subsequent requirement of Risk Management Plan (RMP) submission by certain large chemical facilities to the EPA was mandated within 3 years.
Roth, Stephen T
core  

Construction procedure of pMD19▵rmp::Kan.

, 2014
After subcloning Rmp gene in pMD19-T, forward primer was designed in the 3′-flanking region, and reverse primer was designed in the 5′-flanking region. PCR was conducted to obtain DNA fragment pMD19▵rmp with flanking regions in both terminals, which was ...
Yanli Mao (530225), Rushan Xie (530224), Xiaoping Zhu (285497), Guocai Li (530223), Hongmei Jiao (530227), Kun Xiong (530228), Mingchun Ji (530229), Hua Yan (211621), Shuangxi Liu (530226)   +8 more
core   +1 more source

Real world testing and cost‐effectiveness analysis of subcutaneous EEG (REAL‐ASE): Protocol for a prospective multicentre interventional trial

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a common condition associated with significant morbidity, mortality, and costs. Poor documentation of seizures is a major challenge in epilepsy care. Objective seizure counting with mobile devices may mitigate this challenge and improve patient management.
Matthew McWilliam, Pedro F. Viana, Eren Dursun, Joe Davies, Joel S. Winston, Jessica Agren, Harutomo Hasegawa, Jonas Duun‐Henriksen, Mark P. Richardson   +8 more
wiley   +1 more source

HACCP/RMP Adoption in the New Zealand Meat Industry [PDF]

, 2017
In New Zealand, the Animal Products Act 1999 requires that all animal product primary processing businesses must have a risk management programme (RMP) based on the principles of Hazards Analysis and Critical Control Point (HACCP). However, due to market
Scrimgeour, Frank G., Cao, Kay
core   +1 more source

External RMP effect on locked-mode-like instability in helical plasmas [PDF]

, 2020
0000-0003-3754-897XThe slowing-down mechanism of the locked-mode-like instabilities with and without an island structure is investigated through the effects of an external RMP (resonant magnetic perturbation) on the instabilities. For both instabilities,
YOSHINUMA, Mikiro, WATANABE, Kiyomasa, LHD Experiment Group,, IDA, Katsumi, TAKEMURA, Yuuki, NARUSHIMA, Yoshiro, The LHD Experiment Group,, TAKEMURA, Yuki, OHDACHI, Satoshi, SAKAKIBARA, Satoru, YOSHINUMA, Mikirou   +10 more
core   +1 more source