Results 61 to 70 of about 18,612 (273)

Comparative cytogenetic study in Muscidae flies

Brazilian Journal of Biology
The chromosome modal number in Muscoidea Diptera is 2n = 12, including five pairs of autosomes and one sex chromosome pair. Nevertheless, some species with 2n = 10 chromosomes have been described, all of them from the Muscidae family.
PP. Parise-Maltempi, RMP. Avancini
doaj   +1 more source

RMP promotes the proliferation and radioresistance of esophageal carcinoma [PDF]

Journal of Cancer, 2019
RMP is a RNA polymerase II Subunit RPB-5 associated protein shown to act as an oncogene in several cancer. However, the mechanism of the involvement of RMP in esophageal cancer (EC) remains unclear. We analyzed RMP expression in EC cell lines and EC tissues. The connection between RMP and clinical pathological features of EC was also elucidated.
Chen, Shaomu, Feng, Yu, Zhang, Biao, Chen, Xiaochun, Wei, Wenxiang, Ma, Haitao   +5 more
openaire   +2 more sources

Monitoring Antiseizure Medication Change Using Ultra Long‐Term Electroencephalogram: A Multicenter Study

Annals of Neurology, EarlyView.
Objective Medication dose adjustments are common in treatment‐resistant epilepsy, but lack robust evidence, and patient‐reported seizure diaries have known limitations. We assessed whether ultra long‐term subcutaneous electroencephalogram (sqEEG) improves detection of seizure frequency changes after antiseizure medication adjustments.
Pedro F. Viana, Matthew McWilliam, Johannes Koren, Christina Duarte, Tamara Lisy, Christoph Baumgartner, Karl Rössler, Matthias Tomschik, Adriana Celdrán de Castro, Rodrigo Rocamora, Laura Vilella, Guido Rubboli, Sigge Weisdorf, Cecilia Friedrichs‐Maeder, Troels W. Kjaer, Sanchita Bhatia, Dympna McAleer, Khalid Hamandi, Deborah Spencer, Rajiv Mohanraj, Mark P. Richardson   +20 more
wiley   +1 more source

Neighbors, Drought, and Nitrogen Application Affect the Root Morphological Plasticity of Dalbergia odorifera

Frontiers in Plant Science, 2021
In forest systems, neighbor-induced root morphological plasticity (RMP) is species specific and environment dependent. However, related studies on leguminous woody trees remain sparse.
Li-Shan Xiang, Li-Shan Xiang, Ling-Feng Miao, Ling-Feng Miao, Fan Yang, Fan Yang, Fan Yang   +6 more
doaj   +1 more source

Histology and fossil diagenesis of a pterosaur tooth from the Crato Formation (Lower Cretaceous of Brazil)

The Anatomical Record, EarlyView.
Abstract Pterosaur dental biology remains poorly understood despite its importance for comprehending feeding strategies and flight adaptations. Here, we present the first comprehensive histological analysis of an ornithocheiriform pterosaur tooth from the Lower Cretaceous Crato Formation (Santana Group, Northeast Brazil).
Tito Aureliano, Matheus P. S. Rocha, Francisco P. Lima‐Filho, Aline M. Ghilardi   +3 more
wiley   +1 more source

The mechanism of labor in nonhuman primates: A look inside

The Anatomical Record, EarlyView.
Abstract While in humans, the flexed position of the fetus and its rotating course down the birth canal are well documented, in other primates the mechanism of labor is unknown. Despite the lack of comparative data, it is commonly assumed that the human obstetric mechanism is unique, and anthropologists have disputed when and why the transition to the ...
Melissa K. Stoller
wiley   +1 more source

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Mutations in the rpoB gene of rifampicin-resistant Mycobacterium tuberculosis strains isolated in Brazil and France

Memorias do Instituto Oswaldo Cruz, 2001
We evaluated the mutations in a 193bp of the rpoB gene by automated sequencing of rifampicin (RMP)-resistant and susceptible Mycobacterium tuberculosis strains isolated from Brazil (25 strains) and France (37 strains). In RMP-resistant strains, mutations
S Spindola de Miranda, AL Kritski, I Filliol, C Mabilat, G Panteix, E Drouet   +5 more
doaj   +1 more source

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source