Results 51 to 60 of about 18,612 (273)

Translocation pause of remdesivir-containing primer/template RNA duplex within SARS-CoV-2’s RNA polymerase complexes

Frontiers in Molecular Biosciences, 2022
The mechanism of remdesivir incorporation into the RNA primer by the RNA-dependent RNA polymerase (RdRp) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) remains to be fully established at the molecular level.
Yuanjun Shi, Jimin Wang, Victor S. Batista   +2 more
doaj   +1 more source

The Cost of a Nutritious Diet in Cafeterias: Evidence From US Military Dining Facilities

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Providing nutritious meals in institutional settings with financial constraints, such as military dining facilities, is challenging. The US Department of War (DoW) and US Department of Agriculture (USDA) collaborated to modernize the Basic Daily Food Allowance (BDFA) using an optimization model that incorporates service members' consumption ...
Linlin Fan, Yiwen Zhao, Andrea Carlson, Parke Wilde, Joanna Reagan, Julianna Jayne, Starr Seip, Denise Laursen, Matthew P. Rabbitt   +8 more
wiley   +1 more source

Mitigating unfavourable treatment outcomes and acquired rifampicin resistance in isoniazid-resistant tuberculosis: the role of fluoroquinolone

Journal of Microbiology, Immunology and Infection
Background: Rifampicin (RMP), ethambutol, and pyrazinamide (PZA) for 6–9 months were recommended for the management of isoniazid-resistant, rifampicin-susceptible tuberculosis (Hr-TB), but recommendations on fluoroquinolones (FQs) were inconsistent.
Pin-Hui Lee, Ching-Han Liu, Pei-Chun Chan, Ya-Chun Yang, Po-Wei Chu, Chi-Fang Feng, Hsiu-Yun Lo, Chia-Chi Lee, Chen-Yuan Chiang   +8 more
doaj   +1 more source

Mechanisms of Protective Effect of Ramulus Mori Polysaccharides on Renal Injury in High-Fat Diet/Streptozotocin-Induced Diabetic Rats

Cellular Physiology and Biochemistry, 2015
Background: Diabetic nephropathy (DN) is the most important complication of diabetes and the most common cause of end-stage renal disease (ESRD). Aims: A recent study established that the Ramulus mori polysaccharides (RMP) exert antioxidant effects on DN
Xi Li, Ling Wang, Xingxin Gao, Guoping Li, Honghua Cao, Dezhi Song, Shuangqi Cai, Tao Liang, Bo Zhang, Gang Du   +9 more
doaj   +1 more source

Low awareness of risk mitigation prescribing in response to dual crises of COVID-19 and overdose deaths among people who use unregulated drugs in Vancouver, Canada

Harm Reduction Journal, 2022
Background When the novel coronavirus pandemic emerged in March 2020, many settings across Canada and the USA were already contending with an existing crisis of drug overdoses due to the toxic unregulated drug supply.
Mana Moshkforoush, Kora DeBeck, Rupinder Brar, Nadia Fairbairn, Zishan Cui, M.-J. Milloy, Jane Buxton, Tanis Oldenburger, Will McLellan, Perry Kendall, Kali Sedgemore, Dean Wilson, Thomas Kerr, Kanna Hayashi   +13 more
doaj   +1 more source

Correlations among the plasma concentrations of first-line anti-tuberculosis drugs and the physiological parameters influencing concentrations

Frontiers in Pharmacology, 2023
Background: The plasma concentrations of the four most commonly used first-line anti-tuberculosis (TB) drugs, isoniazid (INH), rifampicin (RMP), ethambutol (EMB), and pyrazinamide (PZA), are often not within the therapeutic range.
Lin Cheng, Ming Luo, Yan Guo, Yunfan Fan, Pengsen Wang, Gang Zhou, Shiwei Qin, Bangbi Weng, Peibo Li, Zhirui Liu, Songtao Liu   +10 more
doaj   +1 more source

Serial backcross analysis of genetic resistance to mousepox, using marker loci for Rmp-2 and Rmp-3 [PDF]

Journal of Virology, 1992
At least three genes from C57BL/6 mice that mediate dominant resistance to lethal mousepox were isolated and transferred onto a susceptible DBA/2 background. Three [(C57BL/6 x DBA/2)F1 x DBA/2] male mice that survived infection were selected as founders on the basis of different complements of marker loci for two resistance genes, Rmp-2r (Hc1) and Rmp ...
D G, Brownstein, P N, Bhatt, L, Gras, T, Budris   +3 more
openaire   +2 more sources

Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cases with congenital heart defects (CHD) often have other associated anomalies. The aim of this investigation was to assess the prevalence and the types of co‐occurring anomalies in CHD in a well‐defined population. The anomalies co‐occurring with CHD were ascertained in all live births, stillbirths and terminations of pregnancy for fetal ...
Claude Stoll, Yves Alembik, Marie‐Paule Roth   +2 more
wiley   +1 more source

Evaluering av RMP-2006. Kulturlandskapstiltak [PDF]

, 2008
Denne evalueringen av kulturlandskapstiltakene i Regionale Miljøprogram (RMP) er utført på oppdrag fra Statens landbruksforvaltning (SLF). Rapporten er en evaluering av RMPs organisering med hensyn på kulturlandskapstiltak.
Puschmann, Oskar, Lågbu, Roar, Reid, Svein Johan   +2 more
core  

Regionalist Parties : CMP/RMP and Gov. Part. [PDF]

, 2019
CMP SPSS and RMP SPSS : converted data from the datasets + other control variables Tables 1 - 4 Descriptives and Binary Logistic Regression Analysis Appendix A + B: Historical overview of regionalist parties and governement participation Appendix C ...
Terriere, L (via Mendeley Data)
core   +1 more source