Results 31 to 40 of about 20,565 (264)

A proposed research misconduct policy for universities and postgraduate colleges in developing countries

Nigerian Postgraduate Medical Journal, 2020
Research misconduct policy (RMP) is a legal document that shows the definitions of the various types of misconduct, describes the inquiry and investigation of allegations, and the appropriate penalties that should be imposed.
Adedoyin Adekunle Adesanya
doaj   +1 more source

Comparative Study on Remineralization and Fluoride Release with Ercr: Ysgg Laser and Non-Thermal Atmospheric Pressure Plasma

Journal of Pharmacy and Bioallied Sciences
Background: Re-mineralizing potential (RMP) involves diffusion of calcium and phosphate (Ca and K) ions through pores of the carious surface and all F varnish release F but not at the same constant rate.
Sonali Waghmode, Pamita Agarwal, Savita Hadakar, Nirma Bharati, Namrata Gaonkar, Hitendra Ramesh Jain   +5 more
doaj   +1 more source

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

Advanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi, Federica Cherchi, Martina Venturini, Federico Tommasi, Sandro Gonzi, Chiara Capacci, Giulia Guarnieri, Pasquale Gallina, Annamaria Morelli, Anna Maria Pugliese   +9 more
wiley   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

Advanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao   +10 more
wiley   +1 more source

Inhibitory kinetics of RMP for TbGMPR.

, 2016
A. Dose-response curves of RMP-mediated inhibition of GMPRs. The activities of TbGMPR at different concentrations of RMP were fitted to the Hill equation to calculate the IC50 value.
Ai Tomiyama (842994), Akira Imamura (219218), Ko Fujimori (308511), Takashi Inui (821466), Takahiro Shinohara (842993), Kazuhiko Nishimura (842995), Chihiro Kimura (842992), Tomoaki Bessho (842990), Osamu Ishibashi (209194), Tetsuya Okada (842991), Satoshi Shuto (102368), Mitsuru Kuwamura (233553), Bruno Kilunga Kubata (328438)   +12 more
core   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

ANALISIS DAN STRATEGI OPTIMALISASI KINERJA MINIMARKET RMP [PDF]

, 2019
Minimarket RMP adalah perusahaan yang bergerak di bidang retail dibawah naungan koperasi syariah. Dalam persaingan bisnis yang semakin sengit, maka Minimarket RMP harus senantiasa memanfaatkan dan mengoptimalkan pemanfaatan peluang yang ada untuk ...
Puspitorini, Pipit Sari,0709127801, Nadhif, Nisfi Fadjri, 51504090033, Rosyida, Erly Ekayanti, 0709038201   +2 more
core   +1 more source

Interaction Of Platelets With Red Cell-Derived Microparticles (RMP): RMP Increase Platelet Aggregate Size In a Shear-Dependent Manner

, 2013
Background Red cell microparticles (RMP) have come to recent attention as putative mediators of hemostasis. We reported that RMP improve hemostatic defect of blood samples of thrombocytopenia and thrombocytopathy and augment platelet function.
Johansen, Max E, Horstman, Larry, Ahn, Yeon S, Jy, Wenche, Perez, Vanessa   +4 more
core   +1 more source

Unravelling the Distinct Phenotype and Mechanosensitive Properties of Different Tendon Cell Populations

Advanced Science, EarlyView.
Tendon interfascicular and fascicular matrix cells are isolated and cultured, revealing distinct phenotypes and mechanosensitive responses. Interfascicular matrix cells exhibit marked stiffness‐dependent phenotypic plasticity, whereas fascicular matrix cells remain comparatively stable.
S. E. Grossemy, D. E. Zamboulis, N. S. Khatib, M. R. Fazal, C. C. Gains, A. Giannopoulos, T. Hopkins, C. Bevan, Y. Aggarwal, M. M. Knight, H. R. C. Screen   +10 more
wiley   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source