Results 171 to 180 of about 959,158 (292)

Tripled-Stranded Antisense Oligonucleotide for Biomarker-Activated Suppression of Essential Genes. [PDF]

Chembiochem
Drozd VS, Tafran L, Zaramenskih NV, Panova YA, Hussein Z, Rybalko DS, Kolpashchikov DM, Eldeeb AA.   +7 more
europepmc   +1 more source

Three‐dimensional observation of the muscle–tendon integration process in mouse embryos

Developmental Dynamics, EarlyView.
Abstract Background Muscle–tendon integration is a crucial step in the morphogenesis of the vertebrate locomotion system. As the limb muscle and tendon progenitor cells derive from distinct embryonic origin, their integration requires precise mutual positioning.
Ramu Sagasaki, Anzu Taniguchi, Shunsuke Oka, Mizuki Mishima, Yuki Yamasaki, Yutaro Kawa, Saundra Schlesinger, Ryo Fujita, Chisa Shukunami, Hiroshi Asahara, Masafumi Inui   +10 more
wiley   +1 more source

Transcriptomic Reprogramming of the Human Placenta Following Maternal Opioid Exposure: Identification of Altered Metabolic and Translational Pathways. [PDF]

Curr Issues Mol Biol
Ng PK, Khadka VS, Howe C, Riel J, Lee MJ, Kendal-Wright CE.   +5 more
europepmc   +1 more source

Influence of mismatched and bulged nucleotides on SNP-preferential RNase H cleavage of RNA-antisense gapmer heteroduplexes. [PDF]

Sci Rep, 2017
Magner D, Biala E, Lisowiec-Wachnicka J, Kierzek R.   +3 more
europepmc   +1 more source

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

Developmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová, Daniel B. Chu, An Nguyen, Yeniko Ta, Jennifer L. Fish, Richard A. Schneider   +5 more
wiley   +1 more source

RNA-Based Therapeutics in Genetic Neurodevelopmental Disorders: Bridging Molecular Genetics and Precision Medicine. [PDF]

Int J Mol Sci
Focșa IO, Iliescu C, Pomeran C, Budișteanu M, Sandu C, Dică AD, Lincă FI, Moțoiescu C, Bârcă D, Minciu I, Craiu D, Rădoi VE.   +11 more
europepmc   +1 more source

MIT/TFE family transcription factors, Mitf and Tfec, redundantly promote pigment cell differentiation and retinal epithelium pigmentation in teleosts

Developmental Dynamics, EarlyView.
Abstract Background Transcription factors of the MIT/TFE family—mitfa, mitfb, and tfec—play essential roles in specifying pigment cells derived from neural crest cells in vertebrates. In teleosts, which possess multiple pigment cell types, these factors exhibit partially redundant but largely distinct functions across different pigment lineages.
James Lister, Keisuke Sugiwaka, Tetsuaki Kimura, Rieko Tanaka, Makoto Goda, Hikaru Kobayashi, Chikako Inoue, Kawilarang W. A. Masengi, Kazunori Yamahira, Kiyoshi Naruse, Satoshi Ansai, Robert N. Kelsh, Masahiko Hibi, Hisashi Hashimoto   +13 more
wiley   +1 more source

ELAVL1 and ELAVL4 Are Required for Musashi-Dependent Translational Activation. [PDF]

Biomolecules
Bronson K, Reddick MM, Macnicol KB, Bolen C, Hardy L, Lagasse A, Odle AK, Childs GV, MacNicol MC, MacNicol AM.   +9 more
europepmc   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

IRES-like element-mediated translation of vsp1S4(-) suppresses BmCPV replication via RNAi antagonism. [PDF]

PLoS Pathog
Chen X, Teng Q, Xue H, Li L, Du X, Zhu M, Zhang X, Gong C, Hu X.   +8 more
europepmc   +1 more source