Results 121 to 130 of about 1,540,463 (333)
Encapsulation state of messenger RNA inside lipid nanoparticles
Biophysical Journal, 2021 M. Brader +5 more
semanticscholar +1 more source
Transcript Identification Using Arrayed Hydrogels With TrapFISH
Advanced Materials Technologies, EarlyView.TrapFISH is a novel method for high‐throughput single‐cell transcriptomics. It embeds cells in hyaluronic acid hydrogel beads and uses probe hybridization to quantify custom gene panels. By arraying hydrogels in microfluidic devices, cell barcoding is removed, enhancing scalability for studying cellular heterogeneity and rare cell states by targeting ...
David B. Morse +5 more
wiley +1 more source
Dynamics of gene expression and the regulatory inference problem
, 2008 From the response to external stimuli to cell division and death, the dynamics of living cells is based on the expression of specific genes at specific times.
+10 more
core +1 more source
Discrimination of messenger RNA [PDF]
FEBS Letters, 1978 Peter Herrlich, Manfred Schweiger
openaire +3 more sources
Advanced Science, EarlyView.The apple susceptibility‐related LRR‐RLK MdRLKT21 competitively binds to fungal sRNA effectors and subsequently activates defenses by salvaging the expression of MdRLKT1 and MdRLKT2 and thereby releasing the resistance protein MdRFP1. These findings provide new insights into the molecular mechanism by which plants counteract pathogen‐secreted sRNA ...
Mingliang Lei +7 more
wiley +1 more source
MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction [PDF]
, 2012 Background: MicroRNA (miRNA) directed gene repression is an important mechanism of posttranscriptional regulation. Comprehensive analyses of how microRNA influence biological processes requires paired miRNA-mRNA expression datasets.
Cauchi, Michael +2 more
core +1 more source
A Mass Spectrometry Approach Reveals Fatty Acid Isomerism in Tomato Cold Tolerance
Advanced Science, EarlyView.An enhanced mass spectrometry approach reveals fatty acids (FAs) and FA isomers that are critical for tomato cold tolerance. Applying specific FA isomers can partially rescue cold sensitivity in tomato mutant plants, highlighting the importance of FA isomers in plant cold stress adaptation.
Leelyn Chong +7 more
wiley +1 more source
Advanced Science, EarlyView.24p3R is an astrocytic receptor for α‐Syn uptake. When LCN2 is secreted from astrocytes, it binds to its receptor 24p3R in astrocytes and this binding impedes the α‐Syn PFF binding to 24p3R. This in turn inhibits 24p3R‐mediated α‐Syn PFF uptake and reduces the clearance of extracellular α‐Syn by astrocytes, which contributes to α‐Syn spread and ...
Ying‐Ying Jiao +14 more
wiley +1 more source
Identification of antisense nucleic acid hybridization sites in mRNA molecules with self-quenching fluorescent reporter molecules [PDF]
, 2005 We describe a physical mRNA mapping strategy employing fluorescent self-quenching reporter molecules (SQRMs) that facilitates the identification of mRNA sequence accessible for hybridization with antisense nucleic acids in vitro and in vivo, real time ...
Do, Bao T. +11 more
core +2 more sources
Advanced Science, EarlyView.Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang +6 more
wiley +1 more source