Results 171 to 180 of about 1,192,406 (301)

PDZ-binding kinase promotes ovarian cancer cell proliferation and invasion via <i>CCNB1</i> regulation. [PDF]

Transl Cancer Res
Awuti G, Wang J, Lu Y, Jiang H, Guo X.
europepmc   +1 more source

Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang   +4 more
wiley   +1 more source

Phase 3 Randomized Study Investigating the Safety, Tolerability, and Immunogenicity of a Combination Modified Messenger RNA Vaccine Against Influenza and COVID-19 in Healthy Adults. [PDF]

Vaccines (Basel)
Puebla YP, Nicholls H, Fitz-Patrick D, Horton LE, Gawel MW, Martinez RD, Wang X, Keep G, Xu X, Gomme E, Scully I, Allen PS, Swanson KA, Salisch N, Mensa FJ, Rizzi R, Türeci Ö, Şahin U, Anderson AS, Gurtman A, Lindert KA.   +20 more
europepmc   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

An mRNA-LNP vaccine expressing TP0435 provides protective immunity in rabbits against <i>Treponema pallidum</i> challenge. [PDF]

Emerg Microbes Infect
Lu Z, Lu Y, Liu D, Du F, Wu Q, Liao G, Wu Y, Zhang RL, Zhou J, Wang QQ.   +9 more
europepmc   +1 more source

Structural mechanism of SAM-AMP and SAM-AMP₂ synthesis by the type III-D2 CRISPR effector complex. [PDF]

Nat Commun
Mitsuda Y, Sugaya M, Ishikawa J, Nagahata N, Okazaki S, Hiraizumi M, Kato K, Gootenberg JS, Abudayyeh OO, Osawa T, Yamashita K, Nishimasu H.   +11 more
europepmc   +1 more source

Overexpression of TCF7L2 promotes the viability and migration of MHCC-97H human hepatocellular carcinoma cells by upregulating MT-ND4L. [PDF]

Transl Cancer Res
Chen R, Liu W, Yang Z, Hao W, Chen B, Zhao S, Zheng L, Lu J.   +7 more
europepmc   +1 more source

Obesity-related palmitic acid exacerbates IL-13-induced mucus phenotype in 16HBE airway epithelial cells via AMPK suppression. [PDF]

Transl Pediatr
Liu Q, Chang X, Jing W, Liu S.
europepmc   +1 more source

Endolysosomal routing combined with immune stimulation enhances anti-tumor efficacy of an HPV16 mRNA therapeutic vaccine. [PDF]

Mater Today Bio
Song W, Ying B, Gao P, Zhang Z, Ma X, Ma J, Yang S, Wu Y, Wu D, Wu J, Du T.   +10 more
europepmc   +1 more source

Identification of a Circular RNA as a Potential Diagnostic and Prognostic Biomarker in Breast Cancer Through Integrated Bioinformatic and Experimental Analyses. [PDF]

Anal Sci Adv
Hashemi M, Morovat P, Khoshghiafeh A, Nikbakhsh N, Ahmadifard M.   +4 more
europepmc   +1 more source