Results 201 to 210 of about 1,347,350 (288)

Deciphering the Potential Causal and Prognostic Relationships Between Gut Microbiota and Brain Tumors: Insights from Genetics Analysis and Machine Learning

Exploration, EarlyView.
The causal relationship between gut microbiota and brain tumors and potential prognostic value of microbiota are still unclear. This study confirmed the causal effects of specific gut microbiota on three common brain tumors and identified microbe‐related genes that are expressed in brain tissue and correlated with the abundance of gut microbiota ...
Changwu Wu, Fushu Luo, Yongye Zhu, Chunbo Liu, Zheng Chen, Xiangyu Wang, Jun Tan, Qing Liu   +7 more
wiley   +1 more source

Alfalfa Flavonoids Mitigate Salmonella‐Induced Colitis via the Keap1‐Nrf2 and TLR4/NF‐κB/COX‐2 Pathways

Food Frontiers, EarlyView.
Alfalfa flavonoids (AF) protected against Salmonella‐induced colitis by reducing inflammation and oxidative stress. AF inhibited the TLR4/IκB/NF‐κB/COX‐2 pathway and NLRP3 inflammasome, lowering pro‐inflammatory cytokines, while activating Keap1‐Nrf2 to boost antioxidants (e.g., HO‐1, NQO1, SOD, GPx), decreasing ROS‐driven oxidative stress.
Xiaoli Qin, Yan Lu, Yawen Luo, Yafang Cui, Kai Zhao, Yang He, Muhammad Aziz ur Rahman, Shengnan Min, Wenfang Wang, Fuyu Yang, Binghai Cao, Huawei Su   +11 more
wiley   +1 more source

The RNA Revolution in the Central Molecular Biology Dogma Evolution. [PDF]

Int J Mol Sci
Haseltine WA, Patarca R.
europepmc   +1 more source

Nanoplatform‐Enabled Genetic Interventions for Central Nervous System Disorders: Advances in Delivery Strategies and Therapeutic Potential

Advanced Genetics, EarlyView.
This review provides a detailed description of gene mutations and epigenetic mechanisms in central nervous system (CNS) disease, strategies for gene therapy, challenges for CNS gene therapy and gene‐drug nanocarriers. This review also summarizes the applications of nanogenetic therapy platforms in CNS diseases (brain tumors, neurodegenerative diseases,
Fuming Liang, Shizhen Cui, Jing Yang, Zhaohui He, Ling Zhu   +4 more
wiley   +1 more source

Engineered circular RNA-based DLL3-targeted CAR-T therapy for small cell lung cancer. [PDF]

Exp Hematol Oncol
Cai J, Liu Z, Chen S, Zhang J, Li H, Wang X, Yang F, Wang S, Li X, Li Y, Chen K, Wang J, Sun M, Qiu M.   +13 more
europepmc   +1 more source

Radioactive Tracing of Testosterone Reveals Minimal Formation of 5α-DHT in SGBS Cells and Human Primary Adipocytes. [PDF]

J Endocr Soc
Andress Huacachino A, Marques CF, Mesaros C, Penning TM.   +3 more
europepmc   +1 more source

Multi-objective computational optimization of human 5' UTR sequences. [PDF]

Brief Bioinform
Yamada K, Suga K, Abe N, Hashimoto K, Tsutsumi S, Inagaki M, Hashiya F, Abe H, Hamada M.   +8 more
europepmc   +1 more source

Pityriasis lichenoides chronica induced by COVID-19 messenger RNA vaccination

JAAD Case Reports, 2022
Abdullah M. Al Muqrin, MD, Ziyad Muharib N. Alruwaili, MD   +1 more
doaj  

Transcriptomic profiling of unmethylated full mutation carriers implicates TET3 in FMR1 CGG repeat expansion methylation dynamics in fragile X syndrome. [PDF]

J Neurodev Disord
Farmiloe G, Bejczy V, Tabolacci E, Willemsen R, Jacobs F.   +4 more
europepmc   +1 more source

Efficient mRNA delivery to resting T cells to reverse HIV latency. [PDF]

Nat Commun
Cevaal PM, Kan S, Fisher BM, Moso MA, Tan A, Liu H, Ali A, Tanaka K, Shepherd RA, Kim Y, Ong J, Furtado DL, Holz M, Purcell DFJ, Casan JML, Payne T, Zhao W, Fareh M, McMahon JH, Deeks SG, Hoh R, Telwatte S, Pouton CW, Johnston APR, Caruso F, Symons J, Lewin SR, Roche M.   +27 more
europepmc   +1 more source