Results 231 to 240 of about 473,581 (304)

Messenger RNA (mRNA) [PDF]

, 2019
openaire   +1 more source

Antiviral regulator TRIM25 as a prognostic marker of better survival in Merkel cell carcinoma: Association with MCPyV status

International Journal of Cancer, EarlyView.
What's New? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt, Sami Kilpinen, Johanna Arola, Benjamin Z. Sundqvist, Tom Böhling, Leif C. Andersson, Harri Sihto   +6 more
wiley   +1 more source

Prokaryotic defense systems: Diversity and evolutionary adaptation. [PDF]

mLife
Yang C, Gong L, Guo J, Xiang H.
europepmc   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, EarlyView.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Investigating the platelet autophagy effect in maintenance hemodialysis patients by whole genome transcriptome from platelets. [PDF]

Medicine (Baltimore)
Lu C, Fan L, Chen H, Zou G, Xie S, Zeng Z, Li Y, Qiu J, Tang D, Dai Y, Yan Q.   +10 more
europepmc   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

TUG1: a potential endogenous reference gene for long noncoding RNA quantification in blood-based studies. [PDF]

Biomark Res
Rodríguez-Muñoz C, Vila A, Santisteve S, Sánchez-Cucó A, Benítez ID, García-Hidalgo MC, Molinero M, Perez-Pons M, Moncusí-Moix A, Barbé F, González J, de Gonzalo-Calvo D.   +11 more
europepmc   +1 more source

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

iNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang, Shuang Wu, Shuangbiao Wei, Weizhen Xiang, Jianshang Huang, Lei Xiong, Hua Wang, Li Zuo   +7 more
wiley   +1 more source

RNA-based co-transfer of human CD8αβ with WT1-specific TCRαβ redirects tumor recognition by CD4 and γδ T-cells towards MHC class I-restricted WT1 epitopes and boosts CD8 T-cell responses with or without CD3 mRNA. [PDF]

Exp Hematol Oncol
Campillo-Davo D, Flumens D, Berneman ZN, Fujiki F, Roex G, Versteven M, Van Acker HH, Van Tendeloo VFI, Sugiyama H, Anguille S, Lion E.   +10 more
europepmc   +1 more source