Results 231 to 240 of about 1,616,912 (329)

Improved Messenger RNA Stability and Biocompatibility Through Self‐Gelatinizable Nucleic Acids

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA‐based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems.
Takumi Tanifuji, Kosuke Kusamori, Chihiro Tanaka, Hideki Sakai, Shoko Itakura, Makiya Nishikawa   +5 more
wiley   +1 more source

Gene, genetics and genetic medicines in gastroenterology: Current status and its future. [PDF]

World J Gastroenterol
Kumar A, Sarangi Y, Kaw P.
europepmc   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Decoding ALS from the tail end of RNA. [PDF]

Cell Genom
Fujioka Y, Ishigaki S.
europepmc   +1 more source

Calcium retinoate nanoparticle mediated microglial polarization to regulate inflammatory microenvironment for therapy of neuroinflammatory disease

BMEMat, EarlyView.
A nano‐drug based on retinoic acid and calcium is developed, which can be rapily endocytosed by microglia and decomposed into small molecule/ion storms in lysosomes. This nano‐drug regulates microglial phenotype switching from M1 to M2 while indirectly guiding neuronal differentiation of endogenous neural stem cells, thereby ameliorating ...
Shuo Zhang, Yuan Yao, Wenfeng Shao, Jiapei Shi, Benjie Wei, Chunhui Sun, Jingang Wang, Jiaming Shi, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Na Ren, Yuchun Tang, Wenjuan Zhou, Shuping Wang   +13 more
wiley   +1 more source

Mapping molluscan endocrinology: a systematic and critical appraisal

Biological Reviews, EarlyView.
ABSTRACT Historically, a vertebrate‐centric paradigm has framed our interpretation of molluscan endocrinology, with considerable research focusing on vertebrate‐type steroid hormones (e.g. oestrogens, testosterone). However, contradictory evidence on the occurrence of vertebrate‐type steroid hormones in molluscan tissues, and a lack of the specific ...
Konstantinos Panagiotidis, Thomas H. Miller, Olwenn V. Martin, Alice Baynes   +3 more
wiley   +1 more source

Sequence-Specific Installation of Aryl Groups in RNA via DNA-Catalyst Conjugates. [PDF]

Angew Chem Int Ed Engl
Pratihar S, Zhong W, Feng S, Chatterjee S, Kool ET.   +4 more
europepmc   +1 more source

Translating Messenger RNA [PDF]

Nature, 1968
openaire   +1 more source

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

, 2003
Ujwal Sheth, R. Parker
semanticscholar   +1 more source

YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA

Cell Research, 2017
Hailing Shi, Xiao Wang, Zhike Lu, B. Zhao, Honghui Ma, Phillip J Hsu, Chang Liu, Chuan He   +7 more
semanticscholar   +1 more source