Tumor Biology, 2017 Insulin-like growth factor 2 messenger RNA-binding proteins have been described to associate with malignant process in many cancers. However, the role of insulin-like growth factor 2 messenger RNA-binding protein family has not been thoroughly elucidated
Run Shi +10 more
doaj +1 more source
Long-Distance Transport of Prosystemin Messenger RNA in Tomato
Frontiers in Plant Science, 2017 Main conclusion: The transcripts of transgenic prosystemin (PS) gene are mobile and the PS mRNA can be translated into protein in tomato and tobacco plants.
Haiyan Zhang, Yuanyuan Hu, Yuanyuan Hu
doaj +1 more source
Optimization of the piggyBac transposon using mRNA and insulators: toward a more reliable gene delivery system. [PDF]
PLoS ONE, 2013 Integrating and expressing stably a transgene into the cellular genome remain major challenges for gene-based therapies and for bioproduction purposes.
Solenne Bire +5 more
doaj +1 more source
Identification of Messenger RNA Signatures in Age-Dependent Renal Impairment
Diagnostics, 2023 In general populations, age-dependent renal impairment contributes to the progression of renal dysfunction. It has not been known which molecules are involved in age-dependent renal impairment.
Katsunori Yanai +5 more
doaj +1 more source
ELAV mediates 3' UTR extension in the Drosophila nervous system
, 2012 Post-transcriptional gene regulation is prevalent in the nervous system, where multiple tiers of regulatory complexity contributeto the development and function of highly specialized cell types.
Hilgers, V., Lemke, S., Levine, M.
core +1 more source
Intracerebral Hemorrhage and Ischemic Stroke of Different Etiologies Have Distinct Alternatively Spliced mRNA Profiles in the Blood: a Pilot RNA-seq Study. [PDF]
, 2015 Whole transcriptome studies have used 3'-biased expression microarrays to study genes regulated in the blood of stroke patients. However, alternatively spliced messenger RNA isoforms have not been investigated for ischemic stroke or intracerebral ...
Ander, Bradley P +8 more
core +2 more sources
Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source
Predictive modeling of plant messenger RNA polyadenylation sites
BMC Bioinformatics, 2007 Background One of the essential processing events during pre-mRNA maturation is the post-transcriptional addition of a polyadenine [poly(A)] tail. The 3'-end poly(A) track protects mRNA from unregulated degradation, and indicates the integrity of mRNA ...
Loke Johnny C +9 more
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a6A-seq: N6-allyladenosine-based cellular messenger RNA metabolic labelling and sequencing
Fundamental Research, 2023 The integration of RNA metabolic labelling by nucleoside analogues with high-throughput RNA sequencing has been harnessed to study RNA dynamics. The immunoprecipitation purification or chemical pulldown technique is generally required to enrich the ...
Xiao Shu +4 more
doaj +1 more source
Messenger RNA Fluctuations and Regulatory RNAs Shape the Dynamics of Negative Feedback Loop
, 2010 Single cell experiments of simple regulatory networks can markedly differ from cell population experiments. Such differences arise from stochastic events in individual cells that are averaged out in cell populations.
Furman, Itay +4 more
core +1 more source