Results 71 to 80 of about 473,734 (283)
Predictive modeling of plant messenger RNA polyadenylation sites
BMC Bioinformatics, 2007 Background One of the essential processing events during pre-mRNA maturation is the post-transcriptional addition of a polyadenine [poly(A)] tail. The 3'-end poly(A) track protects mRNA from unregulated degradation, and indicates the integrity of mRNA ...
Loke Johnny C +9 more
doaj +1 more source
S100B is increased in Parkinson’s disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway [PDF]
, 2012 Peer reviewedPublisher ...
Berg, Daniela +12 more
core +1 more source
, 2021 Messenger RNA medicines are basically sets of instructions and these instructions direct cells in the body to make proteins. mRNA plays a key role in human biology and it is a molecule that carries genetic code from DNA in a cell nucleus to ribosomes the protein making machinery of cells. Messenger RNA carries the genetic information copied from DNA in
openaire +1 more source
Advanced Functional Materials, EarlyView.Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird +8 more
wiley +1 more source
Tumor Biology, 2017 Promoter methylation reflects in the inactivation of different genes like O 6 -methylguanine-DNA methyltransferase DNA repair gene and runt-related transcription factor 3, a known tumor suppressor gene in various cancers such as esophageal cancer.
Snigdha Saikia +9 more
doaj +1 more source
CFIm25 in Solid Tumors: Current Research Progress
Technology in Cancer Research & Treatment, 2020 Cleavage factor I m25 is a newly discovered solid tumor-related gene, however, its precise role in cancer pathogenesis has not yet been characterized.
Xiaojie Sun MD, PhD +4 more
doaj +1 more source
Ribosome reinitiation can explain length-dependent translation of messenger RNA. [PDF]
PLoS Computational Biology, 2017 Models of mRNA translation usually presume that transcripts are linear; upon reaching the end of a transcript each terminating ribosome returns to the cytoplasmic pool before initiating anew on a different transcript.
David W Rogers +3 more
doaj +1 more source
PPM1D phosphatase, a target of p53 and RBM38 RNA-binding protein, inhibits p53 mRNA translation via dephosphorylation of RBM38. [PDF]
, 2015 PPM1D phosphatase, also called wild-type p53-induced phosphatase 1, promotes tumor development by inactivating the p53 tumor suppressor pathway.
Chen, X, Xu, E, Zhang, J, Zhang, M
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Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Advanced Functional Materials, EarlyView.Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras +6 more
wiley +1 more source
Genome-wide analysis of 30 -untranslated regions supports the existence of post-transcriptional regulons controlling gene expression in trypanosomes [PDF]
, 2013 In eukaryotic cells, a group of messenger ribonucleic acids (mRNAs) encoding functionally interrelated proteins together with the trans-acting factors that coordinately modulate their expression is termed a post-transcriptional regulon, due to their ...
Agüero, Fernan Gonzalo +3 more
core +3 more sources